STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lsd-1Lipid storage droplet-1 (Lsd-1) encodes a protein associated with lipid droplets. It protects lipid droplets from lipase mediated remobilization and facilitates lipolysis by serving as an anchoring point for lipases such as the one encoded by Hsl. It is involved in lipid storage amount regulation and energy homeostasis in concert with the product of Lsd-2. (431 aa)    
Predicted Functional Partners:
Hsl
Hormone-sensitive lipase (Hsl) encodes a protein involved in lipid storage.
   
 
 0.714
CG1946
IP08359p; O-acyltransferase activity; diacylglycerol O-acyltransferase activity. It is involved in the biological process described with: triglyceride biosynthetic process; lipid metabolic process.
    
 
 0.633
CG16926
GEO09367p1.
   
    0.632
P5CS
Delta-1-pyrroline-5-carboxylate synthase; Glutamate-5-semialdehyde dehydrogenase activity; glutamate 5-kinase activity; delta1-pyrroline-5-carboxylate synthetase activity. It is involved in the biological process described with: oxidation-reduction process; proline biosynthetic process; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.620
CG1941
RE04845p; O-acyltransferase activity; diacylglycerol O-acyltransferase activity. It is involved in the biological process described with: lipid metabolic process; triglyceride biosynthetic process.
   
 
 0.619
AP-2mu
Adaptor Protein complex 2, mu subunit (AP-2mu) encodes a component of the AP-2 adaptor complex, which recruits certain transmembrane proteins into clathrin-coated pits for endocytic internalization.
    
   0.618
bmm
Brummer, isoform B; Brummer (bmm) encodes a triglyceride lipase involved in glycerolipid metabolism, regulation of lipid storage and triglyceride homeostasis.
   
 
 0.603
CG13607
GH05104p.
   
    0.589
CG2736
GH15894p; Belongs to the CD36 family.
   
 
 0.586
Npc2g
Niemann-Pick type C-2g, isoform A; Sterol binding. It is involved in the biological process described with: intracellular cholesterol transport; sterol transport; mesoderm development.
   
    0.586
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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