STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WsckPutative tyrosine-protein kinase Wsck; Putative receptor with tyrosine-protein kinase activity. (791 aa)    
Predicted Functional Partners:
toy
Twin of eyeless (toy) encodes a transcription factor that is involved in eye development as part of the retinal determination gene network, and contributes to formation of the central nervous system.
      
 0.616
fd3F
Forkhead domain 3F (fd3F) encodes a trancription factor that contributes to the specialization of mechanosensory cilium.
      
 0.500
santa-maria
Scavenger receptor acting in neural tissue and majority of rhodopsin is absent (santa-maria) encodes a class B scavenger receptor that contributes to the conversion of carotenoids to vitamin A. It is involved in phototransduction and thermotaxis; Belongs to the CD36 family.
    
 
 0.495
CG4239
GH25683p; Cation channel activity. It is involved in the biological process described with: monovalent inorganic cation transport.
      
 0.465
Tsp47F
Tetraspanin 47F (Tsp47F) encodes a member of the tetraspanin superfamily of integral membrane proteins that are involved in cell adhesion and signal transduction.
    
 
 0.445
Snmp2
Sensory neuron membrane protein 2; Plays an olfactory role that is not restricted to pheromone sensitivity; Belongs to the CD36 family.
    
 
 0.432
Dh31-R
Diuretic hormone 31 Receptor (Dh31-R) encodes a protein that exhibits diuretic hormone receptor activity. It is involved in G protein-coupled receptor signaling pathwayS; Belongs to the G-protein coupled receptor 2 family.
      
 0.400
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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