STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
baiTransmembrane emp24 domain-containing protein bai; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected; Belongs to the EMP24/GP25L family. (206 aa)    
Predicted Functional Partners:
CHOp24
CHOp24, isoform A; CHOp24 (CHOp24) encodes a p24 transporter that contributes to the intracellular trafficking between the ER and Golgi. It is required for secretion of Wnt ligands.
   
0.996
CG9308
IP11573p; Cargo receptor activity. It is involved in the biological process described with: endoplasmic reticulum to Golgi vesicle-mediated transport; Golgi vesicle transport; intracellular protein transport; Golgi organization.
   
 
 0.990
eca
Transmembrane emp24 domain-containing protein eca; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected. Involved in Golgi organization. Belongs to the EMP24/GP25L family.
   
0.989
p24-2
P24-related-2, isoform A; P24-related-2 (p24-2) encodes a p24-transporter-type protein involved in post-mating oviposition.
   
0.989
p24-1
P24-related-1, isoform A; P24-related-1 (p24-1) encodes a p24 protein that contributes to the secretion of Wnt ligands.
   
0.982
PIG-G
Phosphatidylinositol glycan anchor biosynthesis class G; CP2 mannose-ethanolamine phosphotransferase activity. It is involved in the biological process described with: GPI anchor biosynthetic process.
   
 
 0.946
PGAP1
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. Belongs to the GPI inositol-deacylase family.
    
 
 0.943
deltaCOP
Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.927
opm
Opossum, isoform A; Opossum (opm) encodes a p24 protein that contributes to the secretion of Wnt ligands; Belongs to the EMP24/GP25L family.
   
 
 0.921
loj
Logjam, isoform D; Logjam (loj) encodes a p24-transporter-type protein involved in oviposition.
   
 
 0.872
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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