STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rb97DRibonucleoprotein RB97D; Required for spermatogenesis. Could be required to process a specific transcript essential for spermatogenesis. (471 aa)    
Predicted Functional Partners:
CG4119
BcDNA.LD23634; mRNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome; mRNA splicing, via spliceosome.
   
 
 0.882
CG4896
Uncharacterized protein, isoform D; mRNA binding; RNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome; mRNA splicing, via spliceosome.
   
 
 0.858
Rbp1-like
Rbp1-like, isoform B; Rbp1-like (Rbp1-like) encodes a mRNA binding protein involved in RNA splicing and RNA metabolism.
  
 
 0.795
CG32533
LD31543p; RNA binding; helicase activity. It is involved in the biological process described with: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
   
 
 0.767
rump
Rumpelstiltskin, isoform A; Rumpelstiltskin (rump) encodes the Drosophila hnRNP M homolog. It binds to nos and osk mRNAs and plays a role in mRNA localization to the germ plasm by diffusion/entrapment during late stages of oogenesis. It also binds to exonic splicing enhancers on pre-mRNA targets, implicating it as a splicing factor.
  
 
 0.759
x16
X16 splicing factor (x16) encodes a protein involved in RNA splicing and RNA metabolism regulation.
  
 
 0.727
HnRNP-K
Heterogeneous nuclear ribonucleoprotein K (HnRNP-K) encodes a member of the hnRNP family of DNA/RNA binding proteins. It localizes, along with other hnRNPs, in nucleoplasmic omega speckles. It is involved in gene regulation, post-transcriptional RNA processing and RNA transport.
   
 
 0.716
mahe
Maheshvara, isoform B; Maheshvara (mahe) encodes an RNA helicase.
   
 
 0.713
SC35
SR family splicing factor SC35 (SC35) encodes a mRNA binding protein that regulates mRNA alternative splicing, the processing of the mRNA 3'-end and the selection of the transcriptional start site.
  
 
 0.704
tbrd-2
Testis-specifically expressed bromodomain containing protein-2 (tbrd-2) encodes a protein required for male fertility. It interacts with the products of tbrd-1, tbrd-3 and testis-specific TAFs.
    
 
 0.640
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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