STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cog7Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function. (742 aa)    
Predicted Functional Partners:
Cog3
Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.
   
 0.999
Cog4
Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function.
    
 0.999
Cog8
Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.
   
 0.999
Cog2
Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function.
    
 0.999
Cog1
Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.
   
 0.999
Cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Belongs to the COG6 family.
   
 0.998
fws
Conserved oligomeric Golgi complex subunit 5; Four way stop (fws) encodes a protein localised to the Golgi apparatus and involved in several aspects of spermatogenesis. Loss of function of fws causes failure of cleavage furrow ingression in dividing spermatocytes, as well as failure of cell elongation and disruption of the Golgi-based acroblast during spermatid differentiation.
   
 0.997
Syx5
Syntaxin-5; Syntaxin 5 (Syx5) encodes a type II transmembrane protein in the Q-SNARE family that forms hetero tetramers required for membrane function in the early secretory pathway (ER and Golgi). It has been involved in cytokinesis during spermatogenesis.
     
 0.898
Golgin84
Golgin-84; May be involved in maintaining Golgi structure and in intra- Golgi transport.
      
 0.855
Vps53
Vacuolar protein sorting 53; It is involved in the biological process described with: retrograde transport, endosome to Golgi; endocytic recycling.
   
 
 0.845
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.