STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Jon99CiSerine protease 3; Its major function may be to aid in digestion. (272 aa)    
Predicted Functional Partners:
CG18180
Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.962
Jon25Bii
Jonah 25Bii, isoform A; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.955
Jon25Biii
Jonah 25Biii; Serine-type endopeptidase activity; endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.941
CG17633
Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis; Belongs to the peptidase M14 family.
   
 
 0.891
thetaTry
thetaTrypsin (thetaTry) encodes a putative digestive enzyme with predicted serine-type endopeptidase activity. thetaTry is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the peptidase S1 family.
  
  
0.882
Jon25Bi
Jonah 25Bi; Endopeptidase activity; serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.863
PGRP-SC2
Peptidoglycan recognition protein SC2 (PGRP-SC2) encodes a secreted peptidoglycan recognition protein (PGRP) with an amidase activity against peptidoglycans. It contributes to the down-regulation of the immune deficiency pathway, notably in the fat body during systemic bacterial infection.
   
  
 0.857
LManVI
Alpha-mannosidase activity; carbohydrate binding. It is involved in the biological process described with: protein deglycosylation; mannose metabolic process.
   
    0.856
Jon66Cii
Jonah 66Cii; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.855
Jon99Fii
Jonah 99Fii; Endopeptidase activity; serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.855
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.