STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sry-betaSerendipity locus protein beta; Binds to the consensus DNA sequence 5'-YCAGAGATGCGCA-3'. (356 aa)    
Predicted Functional Partners:
CG4820
Uncharacterized protein; DNA-binding transcription factor activity; zinc ion binding; DNA binding. It is involved in the biological process described with: regulation of gene expression; regulation of transcription, DNA-templated.
  
  
 0.850
CG4730
RE40275p; Transcription regulatory region sequence-specific DNA binding; DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; zinc ion binding. It is involved in the biological process described with: regulation of transcription, DNA-templated.
  
  
 0.839
CG16786
RE48511p.
      
 0.836
CG12219
LD26135p; Zinc ion binding; DNA-binding transcription factor activity; transcription regulatory region sequence-specific DNA binding; DNA binding. It is involved in the biological process described with: regulation of gene expression; regulation of transcription, DNA-templated.
   
  
 0.819
Odj
LD33778p; DNA binding; zinc ion binding. It is involved in the biological process described with: heterochromatin organization involved in chromatin silencing.
  
  
 0.783
tna
Tonalli, isoform B; Tonalli (tna) is an essential gene that encodes several isoforms, including Tna-A, which physically associates with subunits of the Brahma chromatin remodeling complex and is involved in transcriptional activation.
    
 
 0.674
janB
Sex-regulated protein janus-B; JanA and janB regulate somatic sex differentiation.
      
 0.661
Sry-alpha
Serendipity locus protein alpha; Required for the cellularization of the syncytial blastoderm embryo. Involved in the localization of the actin filaments just prior to and during plasma membrane invagination. Sry-alpha together with nullo and bnk may provide auxiliary functions, by acting both to stabilize a large and dynamic microfilament structure and regulate its functions.
 
 
  
 0.488
CG14710
Uncharacterized protein; Zinc ion binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
  
  
0.481
CG6724
Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.
   
  
 0.473
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.