node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG13325 | Npc2c | FBpp0308796 | FBpp0081654 | GH20325p; Transferase activity, transferring acyl groups other than amino-acyl groups. | Niemann-Pick type C-2c; Sterol binding. It is involved in the biological process described with: sterol transport; intracellular cholesterol transport. | 0.533 |
CG13325 | Npc2d | FBpp0308796 | FBpp0081680 | GH20325p; Transferase activity, transferring acyl groups other than amino-acyl groups. | Niemann-Pick type C-2d; Sterol binding. It is involved in the biological process described with: sterol transport; intracellular cholesterol transport. | 0.460 |
CG13325 | Npc2e | FBpp0308796 | FBpp0271877 | GH20325p; Transferase activity, transferring acyl groups other than amino-acyl groups. | Niemann-Pick type C-2e (Npc2e) encodes a protein involved in the immune signaling pathway via interaction with lipopolysaccharide, lipid A, peptidoglycan and lipoteichoic acid. | 0.462 |
CG13325 | Npc2g | FBpp0308796 | FBpp0085085 | GH20325p; Transferase activity, transferring acyl groups other than amino-acyl groups. | Niemann-Pick type C-2g, isoform A; Sterol binding. It is involved in the biological process described with: intracellular cholesterol transport; sterol transport; mesoderm development. | 0.491 |
CG13325 | Npc2h | FBpp0308796 | FBpp0085084 | GH20325p; Transferase activity, transferring acyl groups other than amino-acyl groups. | Niemann-Pick type C-2h (Npc2h) encodes a protein involved in immune signaling via interaction with lipopolysaccharides, lipid A, peptidoglycan and lipoteichoic acid. | 0.537 |
Npc1a | Npc1b | FBpp0079547 | FBpp0076932 | Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. | NPC intracellular cholesterol transporter 1 homolog 1b; Important for cholesterol absorption at the midgut epithelium. Acts only in the early steps of sterol absorption, prior to Npc1a-dependent intracellular sterol trafficking. Belongs to the patched family. | 0.907 |
Npc1a | Npc2a | FBpp0079547 | FBpp0077492 | Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. | NPC intracellular cholesterol transporter 2 homolog a; Functions redundantly with Npc2b in regulating sterol homeostasis and ecdysteroid biosynthesis, probably by controlling the availability of sterol substrate. | 0.999 |
Npc1a | Npc2b | FBpp0079547 | FBpp0082350 | Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. | Niemann-Pick type C-2b, isoform A; Sterol binding. It is involved in the biological process described with: multicellular organism reproduction; ecdysteroid biosynthetic process; intracellular cholesterol transport; sterol transport. | 0.999 |
Npc1a | Npc2c | FBpp0079547 | FBpp0081654 | Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. | Niemann-Pick type C-2c; Sterol binding. It is involved in the biological process described with: sterol transport; intracellular cholesterol transport. | 0.958 |
Npc1a | Npc2d | FBpp0079547 | FBpp0081680 | Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. | Niemann-Pick type C-2d; Sterol binding. It is involved in the biological process described with: sterol transport; intracellular cholesterol transport. | 0.558 |
Npc1a | Npc2e | FBpp0079547 | FBpp0271877 | Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. | Niemann-Pick type C-2e (Npc2e) encodes a protein involved in the immune signaling pathway via interaction with lipopolysaccharide, lipid A, peptidoglycan and lipoteichoic acid. | 0.941 |
Npc1a | Npc2f | FBpp0079547 | FBpp0083933 | Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. | Niemann-Pick type C-2f; Sterol binding. It is involved in the biological process described with: intracellular cholesterol transport; sterol transport. | 0.486 |
Npc1a | Npc2g | FBpp0079547 | FBpp0085085 | Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. | Niemann-Pick type C-2g, isoform A; Sterol binding. It is involved in the biological process described with: intracellular cholesterol transport; sterol transport; mesoderm development. | 0.927 |
Npc1a | Npc2h | FBpp0079547 | FBpp0085084 | Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. | Niemann-Pick type C-2h (Npc2h) encodes a protein involved in immune signaling via interaction with lipopolysaccharides, lipid A, peptidoglycan and lipoteichoic acid. | 0.937 |
Npc1b | Npc1a | FBpp0076932 | FBpp0079547 | NPC intracellular cholesterol transporter 1 homolog 1b; Important for cholesterol absorption at the midgut epithelium. Acts only in the early steps of sterol absorption, prior to Npc1a-dependent intracellular sterol trafficking. Belongs to the patched family. | Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. | 0.907 |
Npc1b | Npc2a | FBpp0076932 | FBpp0077492 | NPC intracellular cholesterol transporter 1 homolog 1b; Important for cholesterol absorption at the midgut epithelium. Acts only in the early steps of sterol absorption, prior to Npc1a-dependent intracellular sterol trafficking. Belongs to the patched family. | NPC intracellular cholesterol transporter 2 homolog a; Functions redundantly with Npc2b in regulating sterol homeostasis and ecdysteroid biosynthesis, probably by controlling the availability of sterol substrate. | 0.942 |
Npc1b | Npc2b | FBpp0076932 | FBpp0082350 | NPC intracellular cholesterol transporter 1 homolog 1b; Important for cholesterol absorption at the midgut epithelium. Acts only in the early steps of sterol absorption, prior to Npc1a-dependent intracellular sterol trafficking. Belongs to the patched family. | Niemann-Pick type C-2b, isoform A; Sterol binding. It is involved in the biological process described with: multicellular organism reproduction; ecdysteroid biosynthetic process; intracellular cholesterol transport; sterol transport. | 0.942 |
Npc1b | Npc2c | FBpp0076932 | FBpp0081654 | NPC intracellular cholesterol transporter 1 homolog 1b; Important for cholesterol absorption at the midgut epithelium. Acts only in the early steps of sterol absorption, prior to Npc1a-dependent intracellular sterol trafficking. Belongs to the patched family. | Niemann-Pick type C-2c; Sterol binding. It is involved in the biological process described with: sterol transport; intracellular cholesterol transport. | 0.939 |
Npc1b | Npc2e | FBpp0076932 | FBpp0271877 | NPC intracellular cholesterol transporter 1 homolog 1b; Important for cholesterol absorption at the midgut epithelium. Acts only in the early steps of sterol absorption, prior to Npc1a-dependent intracellular sterol trafficking. Belongs to the patched family. | Niemann-Pick type C-2e (Npc2e) encodes a protein involved in the immune signaling pathway via interaction with lipopolysaccharide, lipid A, peptidoglycan and lipoteichoic acid. | 0.952 |
Npc1b | Npc2f | FBpp0076932 | FBpp0083933 | NPC intracellular cholesterol transporter 1 homolog 1b; Important for cholesterol absorption at the midgut epithelium. Acts only in the early steps of sterol absorption, prior to Npc1a-dependent intracellular sterol trafficking. Belongs to the patched family. | Niemann-Pick type C-2f; Sterol binding. It is involved in the biological process described with: intracellular cholesterol transport; sterol transport. | 0.467 |