STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG12069UT01108p; cAMP-dependent protein kinase activity; ATP binding. It is involved in the biological process described with: protein kinase A signaling; protein phosphorylation. (356 aa)    
Predicted Functional Partners:
Pka-R2
cAMP-dependent protein kinase type II regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Mediates membrane association by binding to anchoring proteins, such as Akap200. Might play an essential role in the regulation of neuronal activity in the brain.
 
 
 0.990
Pka-R1
Protein kinase, cAMP-dependent, regulatory subunit type 1 (Pka-R1) encodes a cAMP-dependent protein kinase regulator that contributes to actin filament and microtubule organization. It is involved in neuromuscular synaptic transmission, molting and response to ethanol.
 
 
 0.990
CG15543
Uncharacterized protein, isoform A; Cytidylate kinase activity; nucleoside diphosphate kinase activity; ATP binding; adenylate kinase activity. It is involved in the biological process described with: nucleoside diphosphate phosphorylation; purine nucleotide metabolic process; nucleoside triphosphate biosynthetic process.
   
  
 0.940
CG31010
Uncharacterized protein, isoform A.
   
  
 0.928
Muc68Ca
Mucin 68Ca; Extracellular matrix structural constituent.
   
 
 0.842
eIF4E4
Eukaryotic translation initiation factor 4E4 (eIF4E4) encodes a protein involved in translational initiation.
   
  
 0.793
ms(3)76Ca
Male sterile (3) 76Ca.
   
    0.754
for
cGMP-dependent protein kinase, isozyme 2 forms cD4/T1/T3A/T3B; Foraging (for) encodes a serine/threonine kinase and a member of the protein kinase G family. For roles include feeding, locomotion, metabolism, development, olfactory habituation, learning and memory, stress, social behavior, as well as Malpighian tubule, heart, muscle and synaptic function.
  
0.748
CG3222
Uncharacterized protein.
   
    0.741
CG30278
FI08015p.
   
    0.724
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.