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Spn42Da protein (fruit fly) - STRING interaction network
"Spn42Da" - Serpin 42Da, isoform B in Drosophila melanogaster
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Spn42DaSerpin 42Da, isoform B; Serine-type endopeptidase inhibitor activity; cysteine-type endopeptidase inhibitor activity. It is involved in the biological process described with- negative regulation of peptide hormone processing; negative regulation of protein processing; negative regulation of endopeptidase activity; regulation of proteolysis; Belongs to the serpin family (424 aa)    
Predicted Functional Partners:
Ccm3
Cerebral cavernous malformation 3 (Ccm3) is a small scaffolding protein. It forms dimers with GckIII, which is essential to CCM3 function and is thought to promote GckIII activity. In the tracheal system, CCM3 is required specifically in terminal cells, and its loss is associated with tube dilation (208 aa)
           
  0.791
CG7497
CG7497, isoform B; G-protein coupled receptor activity; protein serine/threonine kinase activity. It is involved in the biological process described with- actin filament organization; protein phosphorylation; regulation of cell shape; G-protein coupled receptor signaling pathway (412 aa)
       
 
  0.752
l(2)37Cc
Protein l(2)37Cc; Required for larval metabolism or for the progression of the larva into a pupa (276 aa)
           
  0.705
CG5623
annotation not available (279 aa)
           
  0.699
Bem46
Bem46-like protein; Bem46 (338 aa)
           
  0.699
Fur2
Furin-like protease 2; Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif (1682 aa)
       
 
  0.674
Fur1
Furin-like protease 1, isoforms 1/1-X/2; Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif (1269 aa)
       
 
  0.673
Spn85F
Serpin 85F; Serine-type endopeptidase inhibitor activity. It is involved in the biological process described with- negative regulation of endopeptidase activity; regulation of proteolysis; Belongs to the serpin family (640 aa)
           
  0.607
Papss
PAPS synthetase, isoform D; ATP binding; sulfate adenylyltransferase (ATP) activity; adenylylsulfate kinase activity. It is involved in the biological process described with- imaginal disc-derived wing morphogenesis; sulfate assimilation (657 aa)
           
  0.597
CG5823
CG5823, isoform A; Ubiquitin-protein transferase activity. It is involved in the biological process described with- ER-associated ubiquitin-dependent protein catabolic process; protein ubiquitination; Belongs to the ubiquitin-conjugating enzyme family (283 aa)
           
  0.569
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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