STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG16868VWFA and cache domain-containing protein CG16868; Voltage-gated calcium channel activity. (1449 aa)    
Predicted Functional Partners:
Ca-Ma2d
Ca[2+] channel Muscle-specific alpha2/delta subunit, isoform A; Voltage-gated calcium channel activity.
     
 0.922
CG4587
Uncharacterized protein, isoform H; Voltage-gated calcium channel activity.
     
 0.920
stj
Straightjacket, isoform C; Straightjacket (stj) encodes a voltage-gated calcium channel subunit involved in neuromuscular junction development and autophagosome maturation.
     
 0.855
CG42818
Uncharacterized protein.
      
 0.835
Ca-alpha1D
Voltage-dependent calcium channel type D subunit alpha-1; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Encodes a dihydropyridine- and diltiazem- sensitive current in larval body wall muscle. Vital for embryonic development; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
 0.803
CG11085
IP01054p; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; animal organ development.
      
 0.793
CG12523
RE74758p.
      
 0.793
cac
Voltage-dependent calcium channel type A subunit alpha-1; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, neurotransmitter release, gene expression, cell motility, cell division and cell death (By similarity). Probably encodes a dihydropyridine- insensitive current. Vital for survival to adulthood.
   
 0.769
Rgk2
Rad, Gem/Kir family member 2 (Rgk2) encodes a protein that regulates voltage-gated calcium channel activity.
      
 0.677
ms(2)34Fe
Male sterile (2) 34Fe; It is involved in the biological process described with: spermatid differentiation.
      
 0.669
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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