Lesswright (lwr) encodes Ubc9, a SUMO conjugating enzyme that accepts SUMO from the SUMO activating enzyme and hands it off to the SUMO conjugation target. It has documented biological functions in innate immunity, meiosis, and anterior patterning of the embryo.

RH42110p; RNA binding.

LEM domain-containing protein Bocksbeutel; Inner nuclear membrane protein. May have a role in maintaining the structural integrity of the nuclear lamina. During pupal development, plays essential and redundant functions with the other LEM domain proteins; MAN1 and Ote. Also has a redundant but important role with Ote in larval development.

IP14658p; It is involved in the biological process described with: ribosome biogenesis.

HP1 and insulator partner protein 1 (HIPP1) encodes a chromatin-associated protein, displaying strong protein-protein interaction with the product of Su(var)205. It is localized to pericentric heterochromatin, and potentially has a separate role bound to insulators along with the products of su(Hw), mod(mdg4) and Cp190.

LD24968p; RNA polymerase II regulatory region sequence-specific DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.

SD02086p.

Uncharacterized protein, isoform B.

Vacuolar protein sorting-associated protein 72 homolog; Part of the Tip60 chromatin-remodeling complex which is involved in DNA repair. Upon induction of DNA double-strand breaks, this complex acetylates phosphorylated H2AV in nucleosomes and exchanges it with unmodified H2AV.