STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Idgf5Chitinase-like protein Idgf5; Probably required to stimulate the proliferation, polarization and motility of imaginal disk cells. May act by stabilizing the binding of insulin-like peptides to its receptor through a simultaneous interaction with both molecules to form a multiprotein signaling complex (By similarity); Belongs to the glycosyl hydrolase 18 family. IDGF subfamily. (444 aa)    
Predicted Functional Partners:
CG30338
IP09963p.
      
 0.675
CG15202
Uncharacterized protein, isoform A.
      
 0.675
Gbp2
Growth-blocking peptide 2, isoform A; N-acetyltransferase activity; cytokine activity. It is involved in the biological process described with: signal transduction.
   
    0.617
CG3505
CLIP domain-containing serine protease; It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. CLIP subfamily.
   
  
 0.516
Nepl18
Neprilysin-like 18; Metalloendopeptidase activity. It is involved in the biological process described with: proteolysis.
   
    0.499
fat-spondin
Fat-spondin; Serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: cell adhesion.
   
  
 0.495
Nup37
Nucleoporin Nup37; As part of the nuclear pore complex (NPC), has a role in its assembly and function.
    
   0.473
CG33493
GEO02656p1; It is involved in the biological process described with: defense response to Gram-positive bacterium; defense response to Gram-negative bacterium; antibacterial humoral response; response to hyperoxia.
   
  
 0.451
Nepl14
Neprilysin-like 14; Metalloendopeptidase activity. It is involved in the biological process described with: proteolysis.
   
    0.412
Elal
Elastin-like, isoform A; It is involved in the biological process described with: response to nicotine.
   
   0.412
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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