node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Vha100-1 | Vha100-2 | FBpp0084750 | FBpp0083072 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | 0.900 |
Vha100-1 | Vha100-3 | FBpp0084750 | FBpp0085786 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | 0.762 |
Vha100-1 | Vha16-4 | FBpp0084750 | FBpp0086218 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.977 |
Vha100-1 | Vha26 | FBpp0084750 | FBpp0311965 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit E; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.992 |
Vha100-1 | Vha55 | FBpp0084750 | FBpp0082139 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells; Belongs to the ATPase alpha/beta chains family. | 0.993 |
Vha100-1 | VhaAC39-1 | FBpp0084750 | FBpp0070584 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity); Belongs to the V-ATPase V0D/AC39 subunit family. | 0.997 |
Vha100-1 | VhaAC39-2 | FBpp0084750 | FBpp0083793 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | Probable V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system; Belongs to the V-ATPase V0D/AC39 subunit family. | 0.988 |
Vha100-1 | VhaPPA1-1 | FBpp0084750 | FBpp0082464 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | Vacuolar H[+] ATPase PPA1 subunit 1 (VhaPPA1-1) encodes a protein involved in tracheal terminal branching; Belongs to the V-ATPase proteolipid subunit family. | 0.994 |
Vha100-1 | VhaSFD | FBpp0084750 | FBpp0080495 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). | 0.989 |
Vha100-1 | mt:ATPase6 | FBpp0084750 | FBpp0390630 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] | 0.754 |
Vha100-2 | Vha100-1 | FBpp0083072 | FBpp0084750 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | 0.900 |
Vha100-2 | Vha100-3 | FBpp0083072 | FBpp0085786 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | 0.762 |
Vha100-2 | Vha16-4 | FBpp0083072 | FBpp0086218 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.974 |
Vha100-2 | Vha26 | FBpp0083072 | FBpp0311965 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase subunit E; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.985 |
Vha100-2 | Vha55 | FBpp0083072 | FBpp0082139 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells; Belongs to the ATPase alpha/beta chains family. | 0.991 |
Vha100-2 | VhaAC39-1 | FBpp0083072 | FBpp0070584 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity); Belongs to the V-ATPase V0D/AC39 subunit family. | 0.996 |
Vha100-2 | VhaAC39-2 | FBpp0083072 | FBpp0083793 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | Probable V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system; Belongs to the V-ATPase V0D/AC39 subunit family. | 0.958 |
Vha100-2 | VhaPPA1-1 | FBpp0083072 | FBpp0082464 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | Vacuolar H[+] ATPase PPA1 subunit 1 (VhaPPA1-1) encodes a protein involved in tracheal terminal branching; Belongs to the V-ATPase proteolipid subunit family. | 0.974 |
Vha100-2 | VhaSFD | FBpp0083072 | FBpp0080495 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). | 0.986 |
Vha100-2 | mt:ATPase6 | FBpp0083072 | FBpp0390630 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] | 0.754 |