STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AmyrelAmyrel (Amyrel) encodes an amylolytic activity protein that is expressed mainly in larval midgut. (493 aa)    
Predicted Functional Partners:
AGBE
1,4-Alpha-Glucan Branching Enzyme (AGBE) encodes a protein that is inferred to be a hydrolase involved in glycogen synthesis and hypoxia, based on the function of its orthologs. It contributes to the determination of lifespan.
  
 
 0.956
GlyP
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). Required for glycogen breakdown in skeletal muscle.
  
 0.945
CG9485
Uncharacterized protein, isoform B; 4-alpha-glucanotransferase activity; amylo-alpha-1,6-glucosidase activity. It is involved in the biological process described with: glycogen biosynthetic process; glycogen catabolic process.
  
 0.942
Amy-p
Alpha-amylase B; Amylase proximal (Amy-p) encodes one of three amylases encoded in the Drosophila genome. It is a digestive enzyme required for the hydrolysis of dietary starch.
  
  
0.903
Amy-d
Amylase distal (Amy-d) encodes one of three amylases encoded in the Drosophila genome. It is a digestive enzyme required for the hydrolysis of dietary starch.
  
  
0.902
Mal-A8
Maltase A8; Maltose alpha-glucosidase activity. It is involved in the biological process described with: carbohydrate metabolic process.
   
 
 0.857
Mal-A1
Maltase A1; Maltose alpha-glucosidase activity. It is involved in the biological process described with: carbohydrate metabolic process; Belongs to the glycosyl hydrolase 13 family.
   
 
 0.850
Mal-A7
Maltase A7, isoform A; Maltose alpha-glucosidase activity. It is involved in the biological process described with: carbohydrate metabolic process.
   
 
 0.850
mt:CoII
Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]
      
 0.840
Mal-A4
Maltase A4; Maltose alpha-glucosidase activity. It is involved in the biological process described with: carbohydrate metabolic process.
   
 
 0.834
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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