STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG30324GEO11848p1. (164 aa)    
Predicted Functional Partners:
hale
Hale-bopp.
   
   0.994
ey
Paired box protein Pax-6; Eyeless (ey) encodes a transcription factor that is involved in eye development as part of the retinal determination gene network, and contributes to brain formation.
    
   0.994
dsx
Protein doublesex; Controls somatic sexual differentiation. Binds directly and specifically to the FBE (fat body enhancer) of the yolk protein 1 and 2 genes (Yp1 and Yp2). This enhancer is sufficient to direct the female- specific transcription characteristic of the Yp genes in adult fat bodies. Involved in regulation of male-specific expression of takeout in brain-associated fat body.
    
   0.994
CG31473
AT28215p; FMN binding; pyridoxamine-phosphate oxidase activity. It is involved in the biological process described with: pyridoxine biosynthetic process; pyridoxal phosphate biosynthetic process.
   
    0.507
CG3517
LP03867p.
   
    0.430
Rcd7
Reduction in Cnn dots 7, isoform A; It is involved in the biological process described with: spermatogenesis; centrosome separation.
   
    0.414
Atg8b
Autophagy-related 8b, isoform A; Microtubule binding; protein tag; ubiquitin protein ligase binding; GABA receptor binding. It is involved in the biological process described with: macroautophagy; autophagosome maturation; cellular response to nitrogen starvation; autophagy of mitochondrion; autophagosome assembly.
   
    0.414
CG3222
Uncharacterized protein.
   
    0.412
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.