STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmem131Transmembrane protein 131 homolog. (1567 aa)    
Predicted Functional Partners:
CG34408
Uncharacterized protein, isoform H; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; activation of GTPase activity.
   
  
 0.778
Tango1
Transport and Golgi organization protein 1; Required for protein secretion. May participate in cargo loading by binding to COPII coat subunits and guiding SH3-bound proteins into a growing carrier. At basal transitional ER sites in follicle epithelial cells, mediates the exit of basal membrane protein such as vkg, LanB1 and Trol, from the endoplasmic reticulum (ER) to basal Golgi clusters.
   
  
 0.708
CG13016
FI21814p1.
   
  
 0.638
CG10209
Uncharacterized protein, isoform B; CG10209 encodes a DNA binding nuclear apoptosis-inducing factor involved in the apoptotic process.
   
  
 0.624
CG4880
LD20971p1; ATPase activity; ATP binding. It is involved in the biological process described with: cellular response to misfolded protein.
   
  
 0.610
CG11737
RE12402p; It is involved in the biological process described with: peroxisome organization.
      
 0.609
CG34398
Uncharacterized protein, isoform A.
      
 0.608
CG2921
LD38241p; Protein carboxyl O-methyltransferase activity; phosphatase activity; enzyme binding. It is involved in the biological process described with: protein methylation; regulation of response to DNA damage stimulus.
      
 0.603
CG5262
Transmembrane protein 104 homolog.
      
 0.603
Naa30B
N(Alpha)-acetyltransferase 30 B; Peptide alpha-N-acetyltransferase activity. It is involved in the biological process described with: N-terminal peptidyl-methionine acetylation.
      
 0.575
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.