node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG40439 | Ercc1 | FBpp0110444 | FBpp0086578 | LD05675p. | Nucleotide excision repair protein ERCC1; Ercc1 (Ercc1) encodes the non-catalytic partner of the nuclease encoded by mei-9 that cuts structures formed during DNA repair. The mei-9-Ercc1 heterodimer interacts with the product of mus312 to make meiotic crossovers. The functions of the product of Ercc1 include repair of UV-induced DNA damage, repair of base adducts, a backup pathway for mismatch repair and meiotic recombination. | 0.453 |
CG40439 | Mlh1 | FBpp0110444 | FBpp0087867 | LD05675p. | Mlh1, isoform A; ATP binding; ATPase activity; mismatched DNA binding. It is involved in the biological process described with: mismatch repair. | 0.910 |
CG40439 | Pms2 | FBpp0110444 | FBpp0086520 | LD05675p. | Pms2; Mismatched DNA binding; ATPase activity; ATP binding. It is involved in the biological process described with: mismatch repair. | 0.903 |
CG40439 | tos | FBpp0110444 | FBpp0080675 | LD05675p. | Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity). | 0.616 |
CG46302 | Ercc1 | FBpp0402851 | FBpp0086578 | annotation not available | Nucleotide excision repair protein ERCC1; Ercc1 (Ercc1) encodes the non-catalytic partner of the nuclease encoded by mei-9 that cuts structures formed during DNA repair. The mei-9-Ercc1 heterodimer interacts with the product of mus312 to make meiotic crossovers. The functions of the product of Ercc1 include repair of UV-induced DNA damage, repair of base adducts, a backup pathway for mismatch repair and meiotic recombination. | 0.445 |
CG46302 | Mlh1 | FBpp0402851 | FBpp0087867 | annotation not available | Mlh1, isoform A; ATP binding; ATPase activity; mismatched DNA binding. It is involved in the biological process described with: mismatch repair. | 0.910 |
CG46302 | Pms2 | FBpp0402851 | FBpp0086520 | annotation not available | Pms2; Mismatched DNA binding; ATPase activity; ATP binding. It is involved in the biological process described with: mismatch repair. | 0.903 |
CG46302 | tos | FBpp0402851 | FBpp0080675 | annotation not available | Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity). | 0.616 |
DNApol-delta | Ercc1 | FBpp0075277 | FBpp0086578 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | Nucleotide excision repair protein ERCC1; Ercc1 (Ercc1) encodes the non-catalytic partner of the nuclease encoded by mei-9 that cuts structures formed during DNA repair. The mei-9-Ercc1 heterodimer interacts with the product of mus312 to make meiotic crossovers. The functions of the product of Ercc1 include repair of UV-induced DNA damage, repair of base adducts, a backup pathway for mismatch repair and meiotic recombination. | 0.749 |
DNApol-delta | Mlh1 | FBpp0075277 | FBpp0087867 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | Mlh1, isoform A; ATP binding; ATPase activity; mismatched DNA binding. It is involved in the biological process described with: mismatch repair. | 0.850 |
DNApol-delta | Msh6 | FBpp0075277 | FBpp0075399 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | Probable DNA mismatch repair protein Msh6; Msh6 (Msh6) encodes a heterodimer with the product of spel1 to detect base-base mismatches and small insertion/deletion loops. It then recruits the rest of the mismatch repair machinery. | 0.976 |
DNApol-delta | Pms2 | FBpp0075277 | FBpp0086520 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | Pms2; Mismatched DNA binding; ATPase activity; ATP binding. It is involved in the biological process described with: mismatch repair. | 0.819 |
DNApol-delta | Xpac | FBpp0075277 | FBpp0070638 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | DNA repair protein complementing XP-A cells homolog; Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region (By similarity). Belongs to the XPA family. | 0.763 |
DNApol-delta | spel1 | FBpp0075277 | FBpp0301208 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | DNA mismatch repair protein spellchecker 1; Involved in postreplication mismatch repair. Binds specifically to DNA containing mismatched nucleotides thus providing a target for the excision repair processes characteristic of postreplication mismatch repair (By similarity). | 0.929 |
DNApol-delta | tos | FBpp0075277 | FBpp0080675 | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity). | 0.979 |
Ercc1 | CG40439 | FBpp0086578 | FBpp0110444 | Nucleotide excision repair protein ERCC1; Ercc1 (Ercc1) encodes the non-catalytic partner of the nuclease encoded by mei-9 that cuts structures formed during DNA repair. The mei-9-Ercc1 heterodimer interacts with the product of mus312 to make meiotic crossovers. The functions of the product of Ercc1 include repair of UV-induced DNA damage, repair of base adducts, a backup pathway for mismatch repair and meiotic recombination. | LD05675p. | 0.453 |
Ercc1 | CG46302 | FBpp0086578 | FBpp0402851 | Nucleotide excision repair protein ERCC1; Ercc1 (Ercc1) encodes the non-catalytic partner of the nuclease encoded by mei-9 that cuts structures formed during DNA repair. The mei-9-Ercc1 heterodimer interacts with the product of mus312 to make meiotic crossovers. The functions of the product of Ercc1 include repair of UV-induced DNA damage, repair of base adducts, a backup pathway for mismatch repair and meiotic recombination. | annotation not available | 0.445 |
Ercc1 | DNApol-delta | FBpp0086578 | FBpp0075277 | Nucleotide excision repair protein ERCC1; Ercc1 (Ercc1) encodes the non-catalytic partner of the nuclease encoded by mei-9 that cuts structures formed during DNA repair. The mei-9-Ercc1 heterodimer interacts with the product of mus312 to make meiotic crossovers. The functions of the product of Ercc1 include repair of UV-induced DNA damage, repair of base adducts, a backup pathway for mismatch repair and meiotic recombination. | DNA polymerase delta catalytic subunit; As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity. | 0.749 |
Ercc1 | Mlh1 | FBpp0086578 | FBpp0087867 | Nucleotide excision repair protein ERCC1; Ercc1 (Ercc1) encodes the non-catalytic partner of the nuclease encoded by mei-9 that cuts structures formed during DNA repair. The mei-9-Ercc1 heterodimer interacts with the product of mus312 to make meiotic crossovers. The functions of the product of Ercc1 include repair of UV-induced DNA damage, repair of base adducts, a backup pathway for mismatch repair and meiotic recombination. | Mlh1, isoform A; ATP binding; ATPase activity; mismatched DNA binding. It is involved in the biological process described with: mismatch repair. | 0.907 |
Ercc1 | Msh6 | FBpp0086578 | FBpp0075399 | Nucleotide excision repair protein ERCC1; Ercc1 (Ercc1) encodes the non-catalytic partner of the nuclease encoded by mei-9 that cuts structures formed during DNA repair. The mei-9-Ercc1 heterodimer interacts with the product of mus312 to make meiotic crossovers. The functions of the product of Ercc1 include repair of UV-induced DNA damage, repair of base adducts, a backup pathway for mismatch repair and meiotic recombination. | Probable DNA mismatch repair protein Msh6; Msh6 (Msh6) encodes a heterodimer with the product of spel1 to detect base-base mismatches and small insertion/deletion loops. It then recruits the rest of the mismatch repair machinery. | 0.943 |