STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp6a19Probable cytochrome P450 6a19; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. (503 aa)    
Predicted Functional Partners:
alphaTub67C
Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis.
   
    0.810
Pxt
Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily.
   
    0.769
CG4991
Uncharacterized protein, isoform D; Amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport.
   
    0.751
otu
Protein ovarian tumor locus; Essential for female fertility; germ cell division and differentiation.
   
    0.747
yl
Putative vitellogenin receptor; Involved in uptake of vitellogenin by endocytosis.
   
    0.703
fs(1)M3
Female sterile (1) M3 (fs(1)M3) encodes a protein that is required, along with the products of fs(1)N and clos, for their accumulation at the vitelline membrane and function in vitelline membrane integrity and Torso receptor activation.
   
    0.690
CG6765
Uncharacterized protein, isoform A; Nucleic acid binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
    
 
 0.684
Mos
Mos oncogene (Mos) encodes a kinase that activates the MAPK cascade during oogenesis; Belongs to the protein kinase superfamily.
   
   0.679
CG6927
LD07278p; Neurotransmitter receptor activity; GABA-A receptor activity; extracellular ligand-gated ion channel activity. It is involved in the biological process described with: chemical synaptic transmission; signal transduction; ion transmembrane transport; regulation of membrane potential; nervous system process.
   
    0.645
osk
Maternal effect protein oskar; Organizes the germ plasm and directs localization of the posterior determinant nanos. Oskar protein is required to keep nos RNA and staufen protein at the posterior pole.
   
   0.645
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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