STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tret1-2Facilitated trehalose transporter Tret1-2 homolog; Fails to transport trehalose; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily. (488 aa)    
Predicted Functional Partners:
Tret1-1
Facilitated trehalose transporter Tret1-1; Low-capacity facilitative transporter for trehalose. Does not transport maltose, sucrose or lactose. Mediates the bidirectional transfer of trehalose. Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
  
 
0.732
Cyt-b5-r
Cytochrome b5-related protein; May play a role in muscle cell metabolism.
   
  
 0.679
CG4239
GH25683p; Cation channel activity. It is involved in the biological process described with: monovalent inorganic cation transport.
      
 0.621
phtf
Putative homeodomain transcription factor; May play a role in transcription regulation.
    
 
 0.603
CG32549
Uncharacterized protein, isoform G; 5'-nucleotidase activity.
      
 0.601
Roc2
Regulator of cullins 2 (Roc2) encodes a C2H2 type zinc finger protein that binds specifically to the product of Cul5 and recruits ubiquitin-charged E2 to the CRL5 E3 ubiquitin ligase complex, which functions during oogenesis.
   
  
 0.541
Orct2
Organic cation transporter 2 (Orct2) encodes an organic cation transporter of the major facilitator superfamily, and a transcriptional target of the insulin receptor pathway.
  
   
 0.513
CG31100
Uncharacterized protein, isoform A; Carbohydrate:proton symporter activity. It is involved in the biological process described with: glucose import.
  
  
 
0.510
CG3270
FI13301p; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process; mitochondrial respiratory chain complex I assembly.
   
  
 0.510
Glut3
Glucose transporter type 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane.
  
  
0.504
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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