STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thetaTrythetaTrypsin (thetaTry) encodes a putative digestive enzyme with predicted serine-type endopeptidase activity. thetaTry is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the peptidase S1 family. (262 aa)    
Predicted Functional Partners:
CG17571
Uncharacterized protein, isoform A; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.987
CG17633
Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis; Belongs to the peptidase M14 family.
   
 
 0.957
hiro
GH21114p; Serine-type carboxypeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase S10 family.
   
  
 0.902
baz
Bazooka, isoform B; Bazooka (baz) encodes a scaffold protein that forms a complex with the products of par-6 and aPKC and with other cortical, cytoskeletal and regulatory proteins. It functions in cell polarization pathways in epithelial, neuronal and other cell types.
     
  0.900
CG8560
GH20109p; Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.
   
 
 0.894
CG10472
RE65433p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
 
  
0.892
CG8562
FI02848p; Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.
   
 
 0.886
Jon99Ci
Serine protease 3; Its major function may be to aid in digestion.
  
  
0.882
Jon99Fii
Jonah 99Fii; Endopeptidase activity; serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.877
Jon25Biii
Jonah 25Biii; Serine-type endopeptidase activity; endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.876
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.