STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polyphGlutamate transporter polyphemus; Probable glutamate transporter which transports extracellular glutamate into the cells. Regulates the production of intracellular reactive oxygen species (ROS) probably by controlling the synthesis of antioxidant glutathione. By regulating ROS production in blood cells, required for maintaining bacteria phagocytosis following infection with S.aureus and possibly E.coli; Belongs to the amino acid/polyamine transporter 2 family. (460 aa)    
Predicted Functional Partners:
CG17196
Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation.
   
    0.886
CG14183
GH08353p; ATP binding.
   
  
 0.862
Gpo2
Glycerol-3-phosphate dehydrogenase (quinone) activity; calcium ion binding. It is involved in the biological process described with: glycerol metabolic process; glycerol-3-phosphate metabolic process; oxidation-reduction process; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
   
  
 0.857
PpD5
Protein serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; Belongs to the PPP phosphatase family.
   
   0.855
Rtnl2
Reticulon-like protein.
   
    0.854
CG10164
IP12902p.
   
    0.853
Reepl1
Receptor expression-enhancing protein; It is involved in the biological process described with: endoplasmic reticulum tubular network organization; male germ-line cyst formation.
   
    0.852
CG13032
FI23334p1; It is involved in the biological process described with: non-motile cilium assembly; cytoplasmic microtubule organization.
   
  
 0.852
CG5662
AT01806p; It is involved in the biological process described with: protein targeting to mitochondrion.
   
    0.851
ms(2)34Fe
Male sterile (2) 34Fe; It is involved in the biological process described with: spermatid differentiation.
   
    0.850
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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