| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG31624 | Git | FBpp0310410 | FBpp0087353 | Uncharacterized protein, isoform A; Transcription coregulator activity. | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | 0.812 |
| CG34325 | Git | FBpp0308859 | FBpp0087353 | MIP06432p1; Transcription coregulator activity. | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | 0.812 |
| Fkbp59 | Git | FBpp0309663 | FBpp0087353 | FK506-binding protein 59kD (Fkbp59) encodes a peptidylprolyl isomerase involved in the regulation of calcium transport and phototransduction. | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | 0.776 |
| Git | CG31624 | FBpp0087353 | FBpp0310410 | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | Uncharacterized protein, isoform A; Transcription coregulator activity. | 0.812 |
| Git | CG34325 | FBpp0087353 | FBpp0308859 | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | MIP06432p1; Transcription coregulator activity. | 0.812 |
| Git | Fkbp59 | FBpp0087353 | FBpp0309663 | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | FK506-binding protein 59kD (Fkbp59) encodes a peptidylprolyl isomerase involved in the regulation of calcium transport and phototransduction. | 0.776 |
| Git | Gprk2 | FBpp0087353 | FBpp0085149 | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | G protein-coupled receptor kinase 2 (Gprk2) encodes a member of a family of serine/threonine kinases that modulate G-protein coupled receptors. It is required for female fertility, normal egg shape, and normal egg cAMP levels. It is also implicated in Hedgehog signaling and olfactory rhythmicity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.747 |
| Git | Liprin-alpha | FBpp0087353 | FBpp0302975 | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | Liprin-alpha, isoform E; Liprin-alpha (Liprin-alpha) encodes a scaffolding protein that interacts with the receptor phosphatase Lar. It is involved in synapse morphogenesis and axon guidance. | 0.948 |
| Git | Liprin-gamma | FBpp0087353 | FBpp0112019 | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | Liprin-gamma, isoform C; Liprin-gamma (Liprin-gamma) encodes an adaptor protein that counteracts the functions of the product of Liprin-alpha in photoreceptor axon targeting and the product of Liprin-beta in neuromuscular junction development, potentially through competition for binding partners. | 0.838 |
| Git | Pak | FBpp0087353 | FBpp0306609 | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | P21-activated kinase (Pak) encodes a serine/threonine effector kinase for the small GTPases Rac and the product of Cdc42 involved in cytoskeletal regulation. The product of Pak contributes to growth cone guidance, synaptic development, and epithelial morphogenesis in both the ovary and embryo. | 0.877 |
| Git | Pak3 | FBpp0087353 | FBpp0303080 | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | Non-specific serine/threonine protein kinase; Pak3 (Pak3) encodes a Ser/Thr kinase implicated in myoblast fusion, synapse development, wound healing and border cell migration. It functions downstream of the small Rac GTPases to regulate actin cytoskeletal organization. | 0.713 |
| Git | Pax | FBpp0087353 | FBpp0099871 | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | Paxillin, isoform F; Paxillin (Pax) encodes an adaptor protein that is generally associated with integrins. It is not required for most integrin-mediated adhesion or migration events, but is required for viability beyond pupal stages. It controls the size of some muscles by regulating the rate of cell fusion. | 0.836 |
| Git | RtGEF | FBpp0087353 | FBpp0307723 | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | Rho-type guanine nucleotide exchange factor (RtGEF) encodes a putative Rho-type guanine nucleotide exchange factor for the GTPases encoded by Rac1 and Cdc42. It signals through the sterile-20 kinases encoded by Pak and hpo. The product of RtGEF contributes to regulation of postsynaptic structure, post synaptic muscle development, protein localization and the growth of epithelial tissue. | 0.990 |
| Gprk2 | Git | FBpp0085149 | FBpp0087353 | G protein-coupled receptor kinase 2 (Gprk2) encodes a member of a family of serine/threonine kinases that modulate G-protein coupled receptors. It is required for female fertility, normal egg shape, and normal egg cAMP levels. It is also implicated in Hedgehog signaling and olfactory rhythmicity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | 0.747 |
| Gprk2 | Pax | FBpp0085149 | FBpp0099871 | G protein-coupled receptor kinase 2 (Gprk2) encodes a member of a family of serine/threonine kinases that modulate G-protein coupled receptors. It is required for female fertility, normal egg shape, and normal egg cAMP levels. It is also implicated in Hedgehog signaling and olfactory rhythmicity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | Paxillin, isoform F; Paxillin (Pax) encodes an adaptor protein that is generally associated with integrins. It is not required for most integrin-mediated adhesion or migration events, but is required for viability beyond pupal stages. It controls the size of some muscles by regulating the rate of cell fusion. | 0.551 |
| Gprk2 | RtGEF | FBpp0085149 | FBpp0307723 | G protein-coupled receptor kinase 2 (Gprk2) encodes a member of a family of serine/threonine kinases that modulate G-protein coupled receptors. It is required for female fertility, normal egg shape, and normal egg cAMP levels. It is also implicated in Hedgehog signaling and olfactory rhythmicity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | Rho-type guanine nucleotide exchange factor (RtGEF) encodes a putative Rho-type guanine nucleotide exchange factor for the GTPases encoded by Rac1 and Cdc42. It signals through the sterile-20 kinases encoded by Pak and hpo. The product of RtGEF contributes to regulation of postsynaptic structure, post synaptic muscle development, protein localization and the growth of epithelial tissue. | 0.505 |
| Liprin-alpha | Git | FBpp0302975 | FBpp0087353 | Liprin-alpha, isoform E; Liprin-alpha (Liprin-alpha) encodes a scaffolding protein that interacts with the receptor phosphatase Lar. It is involved in synapse morphogenesis and axon guidance. | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | 0.948 |
| Liprin-alpha | Liprin-gamma | FBpp0302975 | FBpp0112019 | Liprin-alpha, isoform E; Liprin-alpha (Liprin-alpha) encodes a scaffolding protein that interacts with the receptor phosphatase Lar. It is involved in synapse morphogenesis and axon guidance. | Liprin-gamma, isoform C; Liprin-gamma (Liprin-gamma) encodes an adaptor protein that counteracts the functions of the product of Liprin-alpha in photoreceptor axon targeting and the product of Liprin-beta in neuromuscular junction development, potentially through competition for binding partners. | 0.527 |
| Liprin-alpha | Pax | FBpp0302975 | FBpp0099871 | Liprin-alpha, isoform E; Liprin-alpha (Liprin-alpha) encodes a scaffolding protein that interacts with the receptor phosphatase Lar. It is involved in synapse morphogenesis and axon guidance. | Paxillin, isoform F; Paxillin (Pax) encodes an adaptor protein that is generally associated with integrins. It is not required for most integrin-mediated adhesion or migration events, but is required for viability beyond pupal stages. It controls the size of some muscles by regulating the rate of cell fusion. | 0.426 |
| Liprin-gamma | Git | FBpp0112019 | FBpp0087353 | Liprin-gamma, isoform C; Liprin-gamma (Liprin-gamma) encodes an adaptor protein that counteracts the functions of the product of Liprin-alpha in photoreceptor axon targeting and the product of Liprin-beta in neuromuscular junction development, potentially through competition for binding partners. | G protein-coupled receptor kinase interacting ArfGAP (Git) encodes an Arf-GAP that forms a scaffold with the Rho-type guanine nucleotide exchange factor encoded by pix aiding in activation of the kinase encoded by Pak. The product of RtGEF has roles in muscle morphogenesis, synaptic vesicle recycling, and regulation of tissue growth. | 0.838 |