node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AttA | AttD | FBpp0086567 | FBpp0082908 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Attacin-D (AttD) encodes is an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria. | 0.627 |
AttA | CecA1 | FBpp0086567 | FBpp0084977 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family. | 0.912 |
AttA | CecB | FBpp0086567 | FBpp0085002 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family. | 0.930 |
AttA | CecC | FBpp0086567 | FBpp0084980 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Cecropin-C; Cecropin C (CecC) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is strongly expressed at the pupal stage. | 0.970 |
AttA | Def | FBpp0086567 | FBpp0087518 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily. | 0.916 |
AttA | Dif | FBpp0086567 | FBpp0290792 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Dorsal-related immunity factor Dif; Mediates an immune response in larvae. DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1. Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that downregulates Spn27A in response to infection. Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo signaling cascade that regulates dev [...] | 0.609 |
AttA | DptA | FBpp0086567 | FBpp0085802 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Diptericin A (DptA) encodes an immune inducible antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency pathway; Belongs to the attacin/sarcotoxin-2 family. | 0.986 |
AttA | DptB | FBpp0086567 | FBpp0085803 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Diptericin B (DptB) encodes an immune inducible antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency pathway. | 0.999 |
AttA | Mtk | FBpp0086567 | FBpp0086518 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Metchnikowin (Mtk) encodes an antifungal peptide that is secreted from the fat body during the systemic immune response, and is produced by various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency and/or Toll pathways. | 0.991 |
AttA | imd | FBpp0086567 | FBpp0311815 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Protein immune deficiency; Essential for the imd/NF-kappa-B (Imd) humoral and epithelial immune response to Gram-negative bacteria. Functions as an adapter protein that transduces immunity signals from the activation of pathogen recognition receptors (PRRs) by bacterial infection to the Imd signaling pathway. Binding of diaminopimelic acid-type (DAP-type) bacterial peptidoglycans (PGN) causes multimerization or clustering of PGRP receptors which activate the Imd cascade probably by recruiting imd, Fadd and Dredd to the receptor complex. Once in proximity, Dredd cleaves imd in a Fadd-de [...] | 0.836 |
AttD | AttA | FBpp0082908 | FBpp0086567 | Attacin-D (AttD) encodes is an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria. | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | 0.627 |
AttD | CecA1 | FBpp0082908 | FBpp0084977 | Attacin-D (AttD) encodes is an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria. | Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family. | 0.790 |
AttD | CecB | FBpp0082908 | FBpp0085002 | Attacin-D (AttD) encodes is an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria. | Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family. | 0.922 |
AttD | CecC | FBpp0082908 | FBpp0084980 | Attacin-D (AttD) encodes is an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria. | Cecropin-C; Cecropin C (CecC) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is strongly expressed at the pupal stage. | 0.864 |
AttD | Def | FBpp0082908 | FBpp0087518 | Attacin-D (AttD) encodes is an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria. | Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily. | 0.902 |
AttD | Dif | FBpp0082908 | FBpp0290792 | Attacin-D (AttD) encodes is an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria. | Dorsal-related immunity factor Dif; Mediates an immune response in larvae. DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1. Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that downregulates Spn27A in response to infection. Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo signaling cascade that regulates dev [...] | 0.430 |
AttD | DptA | FBpp0082908 | FBpp0085802 | Attacin-D (AttD) encodes is an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria. | Diptericin A (DptA) encodes an immune inducible antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency pathway; Belongs to the attacin/sarcotoxin-2 family. | 0.810 |
AttD | DptB | FBpp0082908 | FBpp0085803 | Attacin-D (AttD) encodes is an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria. | Diptericin B (DptB) encodes an immune inducible antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency pathway. | 0.949 |
AttD | Mtk | FBpp0082908 | FBpp0086518 | Attacin-D (AttD) encodes is an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria. | Metchnikowin (Mtk) encodes an antifungal peptide that is secreted from the fat body during the systemic immune response, and is produced by various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency and/or Toll pathways. | 0.914 |
AttD | imd | FBpp0082908 | FBpp0311815 | Attacin-D (AttD) encodes is an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria. | Protein immune deficiency; Essential for the imd/NF-kappa-B (Imd) humoral and epithelial immune response to Gram-negative bacteria. Functions as an adapter protein that transduces immunity signals from the activation of pathogen recognition receptors (PRRs) by bacterial infection to the Imd signaling pathway. Binding of diaminopimelic acid-type (DAP-type) bacterial peptidoglycans (PGN) causes multimerization or clustering of PGRP receptors which activate the Imd cascade probably by recruiting imd, Fadd and Dredd to the receptor complex. Once in proximity, Dredd cleaves imd in a Fadd-de [...] | 0.677 |