STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG1441Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (517 aa)    
Predicted Functional Partners:
TwdlV
RT04435p; Structural constituent of chitin-based cuticle. It is involved in the biological process described with: chitin-based cuticle development.
   
  
 0.678
CG31750
Uncharacterized protein CG31750.
      
 0.669
cutlet
Cutlet; DNA binding; DNA clamp loader activity; ATP binding. It is involved in the biological process described with: positive regulation of DNA-directed DNA polymerase activity.
      
 0.601
CG17917
Uncharacterized protein.
   
  
 0.601
CG13946
Uncharacterized protein.
      
 0.600
FASN2
Fatty acid synthase 2 (FASN2) encodes an enzyme required for the synthesis of branched/methylated long chain fatty acids that are the precursors of methylated cuticular hydrocarbons.
  
  
 0.542
TwdlW
LD21452p; Structural constituent of chitin-based cuticle. It is involved in the biological process described with: body morphogenesis; chitin-based cuticle development.
   
    0.540
CG42827
CG42827-PC, CG42827-PD; Serine-type endopeptidase inhibitor activity.
      
 0.533
CG42828
BPTI/Kunitz inhibitor domain-containing protein; Serine-type endopeptidase inhibitor activity.
      
 0.533
CAH5
Carbonic anhydrase 5; Hydro-lyase activity; carbonate dehydratase activity; zinc ion binding. It is involved in the biological process described with: one-carbon metabolic process; Belongs to the alpha-carbonic anhydrase family.
      
 0.523
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (26%) [HD]