STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
l(2)k10201Protein lethal(2)k10201; Vital for development. (221 aa)    
Predicted Functional Partners:
CG7137
Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.
   
  
 0.837
CG13151
Uncharacterized protein.
      
 0.836
CG11076
GM15303p.
      
 0.679
NP15.6
GEO04710p1; It is involved in the biological process described with: respiratory electron transport chain.
      
 0.677
CG9666
LD25448p2; Methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation.
   
  
 0.619
CG15443
RH51096p.
   
   0.579
CG4553
FI11059p.
   
  
 0.541
Prp8
pre-mRNA processing factor 8 (Prp8) is an essential gene that encodes the largest and most highly conserved splicing factor. It is a core component of the U5 snRNP, with a key function in pre-mRNA processing catalyzed by the spliceosome.
      
 0.493
GstE7
Glutathione S transferase E7 (GstE7) encodes a cytosolic enzyme that functions in detoxication. It has high catalytic activity with various isothiocyanates and the toxic environmental pollutants 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (DNT).
      
 0.491
CG15715
MIP04739p.
      
 0.491
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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