STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Prp38Pre-mRNA-splicing factor 38; Required for pre-mRNA splicing; Belongs to the PRP38 family. (330 aa)    
Predicted Functional Partners:
Mfap1
Microfibrillar-associated protein 1; Required for pre-mRNA splicing.
   
 
 0.999
Tango4
Transport and golgi organization 4; It is involved in the biological process described with: mRNA splicing, via spliceosome; protein secretion; Golgi organization.
 
 
   0.962
CG11586
MIP29039p; Zinc ion binding; nucleic acid binding. It is involved in the biological process described with: mRNA splicing, via spliceosome.
   
 
 0.949
Prp8
pre-mRNA processing factor 8 (Prp8) is an essential gene that encodes the largest and most highly conserved splicing factor. It is a core component of the U5 snRNP, with a key function in pre-mRNA processing catalyzed by the spliceosome.
   
 
 0.943
ubl
Ubiquitin-like protein 5; Protein tag. It is involved in the biological process described with: mRNA splicing, via spliceosome; cellular protein modification process.
   
 
 0.921
CG1622
FI05227p; It is involved in the biological process described with: mRNA splicing, via spliceosome.
   
 
 
0.904
CG42724
Uncharacterized protein, isoform C; RNA polymerase binding; transcription coregulator activity. It is involved in the biological process described with: mRNA splicing, via spliceosome.
   
 
 0.896
z
Regulatory protein zeste; Zeste (z) encodes a sequence-specific DNA-binding protein. It is often found in the proximal promoter region of many genes where it helps to recruit the BRM nucleosome remodeling complex. It is best known for the pairing-dependent repressive effects produced by some of its mutants on target genes, especially the w gene.
   
 
 0.895
scaf6
SR-related CTD associated factor 6, isoform A; RNA binding. It is involved in the biological process described with: cellular calcium ion homeostasis; RNA processing.
   
 
 0.866
noi
Splicing factor 3A subunit 3; Probable subunit of a splicing factor complex required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (By similarity). Involved in male fertility; Belongs to the SF3A3 family.
   
 
 0.853
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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