node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACC | Vps13 | FBpp0087947 | FBpp0301727 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | 0.626 |
ACC | Vps13B | FBpp0087947 | FBpp0084871 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Vacuolar protein sorting 13B, isoform A; It is involved in the biological process described with: protein targeting to vacuole; protein retention in Golgi apparatus. | 0.440 |
Atg2 | Vps13 | FBpp0305632 | FBpp0301727 | Autophagy-related 2 (Atg2) encodes a protein known to be required for autophagy. | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | 0.876 |
Atg2 | Vps13B | FBpp0305632 | FBpp0084871 | Autophagy-related 2 (Atg2) encodes a protein known to be required for autophagy. | Vacuolar protein sorting 13B, isoform A; It is involved in the biological process described with: protein targeting to vacuole; protein retention in Golgi apparatus. | 0.730 |
CG12025 | CG32191 | FBpp0311531 | FBpp0311532 | RH22148p. | MIP05773p; Sulfuric ester hydrolase activity. | 0.931 |
CG12025 | Vps13 | FBpp0311531 | FBpp0301727 | RH22148p. | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | 0.820 |
CG32191 | CG12025 | FBpp0311532 | FBpp0311531 | MIP05773p; Sulfuric ester hydrolase activity. | RH22148p. | 0.931 |
CG32191 | Vps13 | FBpp0311532 | FBpp0301727 | MIP05773p; Sulfuric ester hydrolase activity. | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | 0.664 |
Vap33 | Vps13 | FBpp0309607 | FBpp0301727 | VAMP-associated protein 33kDa, isoform B; VAMP-associated protein 33kDa (Vap33) encodes a protein that plays a conserved role in synaptic homeostasis. It controls a number of processes which depend on phosphoinositide levels, such as synaptic growth and axonal transport. It binds to the product of Sac1 to maintain normal levels of phosphoinositides and to the product of Dscam1 to affect its localization within axonal projections. | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | 0.643 |
Vap33 | Vps13B | FBpp0309607 | FBpp0084871 | VAMP-associated protein 33kDa, isoform B; VAMP-associated protein 33kDa (Vap33) encodes a protein that plays a conserved role in synaptic homeostasis. It controls a number of processes which depend on phosphoinositide levels, such as synaptic growth and axonal transport. It binds to the product of Sac1 to maintain normal levels of phosphoinositides and to the product of Dscam1 to affect its localization within axonal projections. | Vacuolar protein sorting 13B, isoform A; It is involved in the biological process described with: protein targeting to vacuole; protein retention in Golgi apparatus. | 0.526 |
Vps13 | ACC | FBpp0301727 | FBpp0087947 | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | 0.626 |
Vps13 | Atg2 | FBpp0301727 | FBpp0305632 | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | Autophagy-related 2 (Atg2) encodes a protein known to be required for autophagy. | 0.876 |
Vps13 | CG12025 | FBpp0301727 | FBpp0311531 | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | RH22148p. | 0.820 |
Vps13 | CG32191 | FBpp0301727 | FBpp0311532 | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | MIP05773p; Sulfuric ester hydrolase activity. | 0.664 |
Vps13 | Vap33 | FBpp0301727 | FBpp0309607 | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | VAMP-associated protein 33kDa, isoform B; VAMP-associated protein 33kDa (Vap33) encodes a protein that plays a conserved role in synaptic homeostasis. It controls a number of processes which depend on phosphoinositide levels, such as synaptic growth and axonal transport. It binds to the product of Sac1 to maintain normal levels of phosphoinositides and to the product of Dscam1 to affect its localization within axonal projections. | 0.643 |
Vps13 | Vps13B | FBpp0301727 | FBpp0084871 | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | Vacuolar protein sorting 13B, isoform A; It is involved in the biological process described with: protein targeting to vacuole; protein retention in Golgi apparatus. | 0.637 |
Vps13 | Vps35 | FBpp0301727 | FBpp0071685 | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | Vacuolar protein sorting 35 (Vps35) encodes a component of the retromer complex that acts to recycle membrane proteins to the Golgi or plasma membrane from endocytosed vesicles. | 0.800 |
Vps13 | Vps39 | FBpp0301727 | FBpp0083022 | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | Vacuolar protein sorting 39 (Vps39) encodes a subunit of the homotypic fusion and vacuole protein sorting (HOPS) complex required for autophagosome maturation. | 0.667 |
Vps13 | anne | FBpp0301727 | FBpp0112329 | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | Nucleotide binding; ATPase activity. It is involved in the biological process described with: cellular calcium ion homeostasis; cation transport; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. | 0.620 |
Vps13 | aux | FBpp0301727 | FBpp0078604 | Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway. | Auxilin, isoform A; Auxilin (aux) encodes a co-factor for the ATPase Hsc70 that regulates Clathrin dynamics. It regulates Notch signaling, eye morphogenesis, sperm individualization and neuron death. | 0.800 |