STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pgant3Polypeptide N-acetylgalactosaminyltransferase 3; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Prefers EA2 as substrate. Has weak activity toward Muc5AC-3, -13 and -3/13 substrates. Plays a critical role in the regulation [...] (667 aa)    
Predicted Functional Partners:
CG34056
IP12857p; Beta-1,3-galactosyltransferase activity; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. It is involved in the biological process described with: protein glycosylation; O-glycan processing, core 1.
     
 0.879
Tsp42Eq
Tetraspanin 42Eq; Belongs to the tetraspanin (TM4SF) family.
 
    
 0.866
CG8708
RE41083p; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; beta-1,3-galactosyltransferase activity. It is involved in the biological process described with: O-glycan processing, core 1; protein glycosylation.
     
 0.859
Tig
Tiggrin (Tig) is an extracellular matrix protein and integrin ligand that accumulates at the embryonic and larval muscle attachment site. It is also found as a component of the hemolymph clot.
    
 
 0.850
C1GalTA
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Core 1 Galactosyltransferase A (C1GalTA) encodes a protein that exhibits strong core 1beta1,3GalT activity, and is involved in the synthesis of T antigen in hemocytes. Its roles include hematopoietic stem cell maintenance, neural network and neuromuscular junction formation.
   
 
 0.842
Tsp42Ep
Tetraspanin 42Ep, isoform A; Belongs to the tetraspanin (TM4SF) family.
      
 0.836
Muc30E
Mucin 30E; Extracellular matrix structural constituent.
      
 0.670
CG2975
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; beta-1,3-galactosyltransferase activity. It is involved in the biological process described with: multicellular organism reproduction; protein glycosylation; O-glycan processing, core 1.
     
 0.656
CG3119
IP15602p; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. It is involved in the biological process described with: O-glycan processing, core 1.
     
 0.656
CG34057
Uncharacterized protein, isoform A; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. It is involved in the biological process described with: O-glycan processing, core 1.
     
 0.656
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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