Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| 7B2 | Pal2 | FBpp0100150 | FBpp0312237 | 7B2, isoform B; 7B2 (7B2) encodes a peptidase required for the zymogen conversion and secretion of the prohormone convertase 2 encoded by amon. | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | 0.759 |
| 7B2 | amon | FBpp0100150 | FBpp0084420 | 7B2, isoform B; 7B2 (7B2) encodes a peptidase required for the zymogen conversion and secretion of the prohormone convertase 2 encoded by amon. | Amontillado (amon) encodes a member of the Prohormone Convertase (PC) family of proteolytic enzymes. PCs generally recognize conserved basic amino acid sequences within protein precursors to direct catalysis of specific cleavage. amon product directly cleaves sli protein and may also target the propeptide encoded by Akh. It is also required for the production of bioactive neuropeptide hormones (e.g. those encoded by Hug, Crz, Ms, Capa and sNPF); Belongs to the peptidase S8 family. | 0.980 |
| CG4577 | Pal2 | FBpp0304560 | FBpp0312237 | Uncharacterized protein, isoform B. | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | 0.442 |
| Pal2 | 7B2 | FBpp0312237 | FBpp0100150 | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | 7B2, isoform B; 7B2 (7B2) encodes a peptidase required for the zymogen conversion and secretion of the prohormone convertase 2 encoded by amon. | 0.759 |
| Pal2 | CG4577 | FBpp0312237 | FBpp0304560 | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | Uncharacterized protein, isoform B. | 0.442 |
| Pal2 | Phm | FBpp0312237 | FBpp0072112 | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | Peptidylglycine alpha-hydroxylating monooxygenase; Monooxygenase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Produces an unstable peptidyl(2- hydroxyglycine) intermediate. C-terminal amidation of peptides is required for normal developmental transitions and for biosynthesis of secretory peptides throughout the life; Belongs to the copper type II ascorbate-dependent monooxygenase family. | 0.973 |
| Pal2 | Ranbp16 | FBpp0312237 | FBpp0292664 | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | Ran-binding protein 16; May function as a nuclear transport receptor. | 0.420 |
| Pal2 | amon | FBpp0312237 | FBpp0084420 | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | Amontillado (amon) encodes a member of the Prohormone Convertase (PC) family of proteolytic enzymes. PCs generally recognize conserved basic amino acid sequences within protein precursors to direct catalysis of specific cleavage. amon product directly cleaves sli protein and may also target the propeptide encoded by Akh. It is also required for the production of bioactive neuropeptide hormones (e.g. those encoded by Hug, Crz, Ms, Capa and sNPF); Belongs to the peptidase S8 family. | 0.510 |
| Pal2 | dimm | FBpp0312237 | FBpp0305546 | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | Protein dimmed; Transcription factor that regulates neurosecretory (NS) cell function and neuroendocrine cell fate. Acts as a master regulator of common NS functions such as Phm expression and neuropeptide production. Plays a role as a regulator of peptide-containing large dense-core vesicle (LDCV) production and peptidergic cell differentiation. Controls transcription of FMRFamide in Tv neuronal cells and Fur1 in Ap-let cells (Tvb and dorsal apterous cells). Also required for up- regulation of Phm in Tv and Ap-let cells, and expression of three neuropeptide genes, Ms, FMRFamide and Lk [...] | 0.449 |
| Pal2 | mEFTu2 | FBpp0312237 | FBpp0088054 | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | Mitochondrial translation elongation factor Tu 2 (mEFTu2) encodes a protein predicted to function within mitochondria to bring aminoacyl-tRNA to the ribosome during the elongation phase of mRNA translation. Unlike the protein encoded by mEFTu1, mEFTu2 product is enriched in the testis, suggesting a testis-specific role for this factor. | 0.461 |
| Pal2 | snky | FBpp0312237 | FBpp0306188 | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | Protein sneaky; Component of the sperm acrosome membrane. Required for breakdown of the sperm plasma membrane after sperm entry into the egg, which is an essential prerequisite for successful fertilization. | 0.430 |
| Pal2 | spab | FBpp0312237 | FBpp0087752 | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | Space blanket. | 0.531 |
| Pal2 | svr | FBpp0312237 | FBpp0089126 | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | Carboxypeptidase D; Required for the proper melanization and sclerotization of the cuticle; Belongs to the peptidase M14 family. | 0.557 |
| Phm | Pal2 | FBpp0072112 | FBpp0312237 | Peptidylglycine alpha-hydroxylating monooxygenase; Monooxygenase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Produces an unstable peptidyl(2- hydroxyglycine) intermediate. C-terminal amidation of peptides is required for normal developmental transitions and for biosynthesis of secretory peptides throughout the life; Belongs to the copper type II ascorbate-dependent monooxygenase family. | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | 0.973 |
| Phm | dimm | FBpp0072112 | FBpp0305546 | Peptidylglycine alpha-hydroxylating monooxygenase; Monooxygenase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Produces an unstable peptidyl(2- hydroxyglycine) intermediate. C-terminal amidation of peptides is required for normal developmental transitions and for biosynthesis of secretory peptides throughout the life; Belongs to the copper type II ascorbate-dependent monooxygenase family. | Protein dimmed; Transcription factor that regulates neurosecretory (NS) cell function and neuroendocrine cell fate. Acts as a master regulator of common NS functions such as Phm expression and neuropeptide production. Plays a role as a regulator of peptide-containing large dense-core vesicle (LDCV) production and peptidergic cell differentiation. Controls transcription of FMRFamide in Tv neuronal cells and Fur1 in Ap-let cells (Tvb and dorsal apterous cells). Also required for up- regulation of Phm in Tv and Ap-let cells, and expression of three neuropeptide genes, Ms, FMRFamide and Lk [...] | 0.834 |
| Phm | spab | FBpp0072112 | FBpp0087752 | Peptidylglycine alpha-hydroxylating monooxygenase; Monooxygenase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Produces an unstable peptidyl(2- hydroxyglycine) intermediate. C-terminal amidation of peptides is required for normal developmental transitions and for biosynthesis of secretory peptides throughout the life; Belongs to the copper type II ascorbate-dependent monooxygenase family. | Space blanket. | 0.450 |
| Ranbp16 | Pal2 | FBpp0292664 | FBpp0312237 | Ran-binding protein 16; May function as a nuclear transport receptor. | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | 0.420 |
| amon | 7B2 | FBpp0084420 | FBpp0100150 | Amontillado (amon) encodes a member of the Prohormone Convertase (PC) family of proteolytic enzymes. PCs generally recognize conserved basic amino acid sequences within protein precursors to direct catalysis of specific cleavage. amon product directly cleaves sli protein and may also target the propeptide encoded by Akh. It is also required for the production of bioactive neuropeptide hormones (e.g. those encoded by Hug, Crz, Ms, Capa and sNPF); Belongs to the peptidase S8 family. | 7B2, isoform B; 7B2 (7B2) encodes a peptidase required for the zymogen conversion and secretion of the prohormone convertase 2 encoded by amon. | 0.980 |
| amon | Pal2 | FBpp0084420 | FBpp0312237 | Amontillado (amon) encodes a member of the Prohormone Convertase (PC) family of proteolytic enzymes. PCs generally recognize conserved basic amino acid sequences within protein precursors to direct catalysis of specific cleavage. amon product directly cleaves sli protein and may also target the propeptide encoded by Akh. It is also required for the production of bioactive neuropeptide hormones (e.g. those encoded by Hug, Crz, Ms, Capa and sNPF); Belongs to the peptidase S8 family. | Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 2; Probable lyase that catalyzes an essential reaction in C- terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. | 0.510 |
| amon | dimm | FBpp0084420 | FBpp0305546 | Amontillado (amon) encodes a member of the Prohormone Convertase (PC) family of proteolytic enzymes. PCs generally recognize conserved basic amino acid sequences within protein precursors to direct catalysis of specific cleavage. amon product directly cleaves sli protein and may also target the propeptide encoded by Akh. It is also required for the production of bioactive neuropeptide hormones (e.g. those encoded by Hug, Crz, Ms, Capa and sNPF); Belongs to the peptidase S8 family. | Protein dimmed; Transcription factor that regulates neurosecretory (NS) cell function and neuroendocrine cell fate. Acts as a master regulator of common NS functions such as Phm expression and neuropeptide production. Plays a role as a regulator of peptide-containing large dense-core vesicle (LDCV) production and peptidergic cell differentiation. Controls transcription of FMRFamide in Tv neuronal cells and Fur1 in Ap-let cells (Tvb and dorsal apterous cells). Also required for up- regulation of Phm in Tv and Ap-let cells, and expression of three neuropeptide genes, Ms, FMRFamide and Lk [...] | 0.437 |
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