STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AnxB9Annexin B9; Calcium-dependent phospholipid binding; calcium ion binding; protein binding; spectrin binding. It is involved in the biological process described with: endosome transport via multivesicular body sorting pathway; maintenance of cell polarity; wing disc dorsal/ventral pattern formation. (324 aa)    
Predicted Functional Partners:
CG1572
LD04844p; It is involved in the biological process described with: positive regulation of hemocyte proliferation.
   
  
 0.730
LamC
Lamin-C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin (By similarity). In spermatocytes, regulates cytokinesis during meiosis.
   
 
 0.524
CG44325
Uncharacterized protein, isoform D; It is involved in the biological process described with: septate junction assembly.
   
  
 0.501
RhoGEF3
Rho guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of Rho protein signal transduction; actin cytoskeleton reorganization; melanotic encapsulation of foreign target; response to wounding; wound healing.
      
 0.497
Swip-1
EF-hand domain-containing protein D2 homolog; Swiprosin-1 (Swip-1) encodes a calcium binding protein, expressed in fusion competent myoblasts and macrophages of the embryo.
   
  
 0.475
galectin
Galectin (galectin) encodes a galactoside binding protein involved in synaptic target recognition.
   
 
 0.459
GILT1
GILT-like protein 1; Involved in the immune response to bacterial infection.
   
  
 0.455
CG12065
Uncharacterized protein, isoform A; Catalytic activity. It is involved in the biological process described with: nucleoside metabolic process.
   
  
 0.446
kst
Karst, isoform E; Karst (kst) encodes a protein that, together with the product of alpha-Spec, crosslinks F-actin and acts as a molecular scaffold. It is recruited to the apical membrane of epithelial cells by the apical determinant encoded by crb. The roles of the product of kst include endosomal trafficking, cell adhesion, cell signaling and growth control.
   
 
 0.441
Gdap2
Protein GDAP2 homolog.
   
 
 0.440
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.