STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Start1Steroidogenic acute regulatory protein-like; May bind to and transport cholesterol and may play a role in ecdysteroid biosynthesis. (583 aa)    
Predicted Functional Partners:
CG33523
Uncharacterized protein, isoform F.
    
 
 0.907
Vap33
VAMP-associated protein 33kDa, isoform B; VAMP-associated protein 33kDa (Vap33) encodes a protein that plays a conserved role in synaptic homeostasis. It controls a number of processes which depend on phosphoinositide levels, such as synaptic growth and axonal transport. It binds to the product of Sac1 to maintain normal levels of phosphoinositides and to the product of Dscam1 to affect its localization within axonal projections.
   
 
 0.813
fan
Farinelli (fan) encodes an important protein for sperm development that interacts with the product of Osbp.
    
 
 0.811
CG32407
Uncharacterized protein, isoform A.
    
 
 0.791
cert
Ceramide transfer protein (cert) encodes a protein involved in determination of lifespan. Mutant flies present accelerated aging due to oxidative stress.
   
  
 0.727
CG1998
RE26969p; Iron ion binding; oxidoreductase activity; C-4 methylsterol oxidase activity. It is involved in the biological process described with: sterol biosynthetic process; oxidation-reduction process; Belongs to the sterol desaturase family.
   
  
 0.671
CG6565
LD05321p; Lipid binding.
      
 0.643
ScpX
Sterol carrier protein X-related thiolase; Transferase activity, transferring acyl groups other than amino-acyl groups; phospholipid transporter activity. It is involved in the biological process described with: positive regulation of intracellular cholesterol transport; phospholipid transport; Belongs to the thiolase-like superfamily. Thiolase family.
   
  
 0.613
nvd
Rieske-domain protein Neverland; Neverland (nvd) encodes an evolutionarily conserved oxygenase-like protein that is required for the biosynthesis pathway of ecdysone. It converts cholesterol to 7-dehydrocholesterol.
      
 0.611
cv-c
Crossveinless c (cv-c) encodes a RhoGTPase activating protein required for the morphogenesis of many tissues through the regulation of actin organization and localization of basement membrane receptors. It regulates synaptic homeostasis at the neuromuscular junction and is required for sleep homeostasis.
      
 0.608
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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