STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Naa60N-alpha-acetyltransferase 60; Displays alpha (N-terminal) acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. [Isoform B]: Does not show histone acetyltransferase activity toward free histones; Belongs to the acetyltransferase family. NAA60 subfamily. (276 aa)    
Predicted Functional Partners:
Naa15-16
N(Alpha)-acetyltransferase 15/16, isoform A; Peptide alpha-N-acetyltransferase activity. It is involved in the biological process described with: N-terminal peptidyl-methionine acetylation.
   
 
 0.883
Naa40
N(Alpha)-acetyltransferase 40; peptide-serine-N-acetyltransferase activity; H4 histone acetyltransferase activity; peptide alpha-N-acetyltransferase activity; H2A histone acetyltransferase activity. It is involved in the biological process described with: regulation of ribosomal DNA heterochromatin assembly; N-terminal protein amino acid acetylation.
      
 0.841
vnc
Variable nurse cells (vnc) encodes a protein involved in histone acetylation and oogenesis.
   
 
 0.801
CG42455
GEO02452p1.
   
 
 0.801
Naa80
N-alpha-acetyltransferase 80; N-alpha-acetyltransferase that acetylates the amino terminal acidic residue of proteins devoid of initiator methionine. Preferentially acts on proteins starting with Asp- Asp-Asp and Glu-Glu-Glu sequences. In vitro, shows high activity towards N-terminal sequences starting with Met-Asp-Glu- Leu, Met-Glu-Glu-Glu and Met-Asp-Asp-Asp.
   
  
 0.759
CG9922
GEO07882p1; It is involved in the biological process described with: protein stabilization; negative regulation of apoptotic process.
   
 
 0.751
Cdc5
Cell division cycle 5, isoform A; DNA binding; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome.
    
   0.684
CG33108
UPF0692 protein CG33108; Belongs to the UPF0692 family.
   
  
 0.669
CG11839
Uncharacterized protein; Zinc ion binding; nucleic acid binding. It is involved in the biological process described with: mitotic cell cycle; replication fork protection; mitotic DNA replication checkpoint; nuclear DNA replication; mitotic DNA damage checkpoint.
      
 0.665
CG8155
LD02690p; CG8155 encodes a Rab GTPase activator of the Rab signaling pathway. It's involved in border follicle cell migration, regulation of GTPase activity, intracellular trafficking of vesicles and determination of lifespan.
   
    0.587
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.