STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CkIIbetaCasein kinase II beta subunit (CkIIbeta) encodes the regulatory subunit of the CKII holoenzyme, a protein serine/threonine kinase composed of a and b subunits. Interactions have been reported with other kinases (e.g., the products of PIP4K and S6kII), the RNA-binding protein encoded by orb , the Hedgehog signaling pathway and clock proteins such as the products of tim and per. The product of CkIIbeta functions in oogenesis, neurogenesis, development (brain and other tissues) as well as circadian behavior. (235 aa)    
Predicted Functional Partners:
CkIIalpha
Casein kinase II subunit alpha; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site. May participate in Wnt signaling; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.
   
 0.999
Ste:CG33242
Ste:CG33242; Protein kinase regulator activity. It is involved in the biological process described with: regulation of protein serine/threonine phosphatase activity.
  
  
 
0.907
Ste:CG33236
Stellate protein CG33236/CG33240/CG33244/CG33245; Unknown. In males lacking the Y chromosome, its strong overexpression leads to the appearance of proteinaceous star-shaped crystals in the primary spermatocytes causing meiotic drive, possibly by interfering with normal casein kinase 2 activity.
  
  
 
0.905
Ste:CG33237
Stellate protein CG33237; Unknown. In males lacking the Y chromosome, its strong overexpression leads to the appearance of proteinaceous star-shaped crystals in the primary spermatocytes causing meiotic drive, possibly by interfering with normal casein kinase 2 activity.
  
  
 
0.905
Ste:CG33238
Stellate protein CG33238; Unknown. In males lacking the Y chromosome, its strong overexpression leads to the appearance of proteinaceous star-shaped crystals in the primary spermatocytes causing meiotic drive, possibly by interfering with normal casein kinase 2 activity.
  
  
 
0.905
Ste:CG33239
Stellate protein CG33239/CG33241; Unknown. In males lacking the Y chromosome, its strong overexpression leads to the appearance of proteinaceous star-shaped crystals in the primary spermatocytes causing meiotic drive, possibly by interfering with normal casein kinase 2 activity.
  
  
 
0.905
Ste:CG33240
Protein kinase regulator activity. It is involved in the biological process described with: regulation of protein serine/threonine phosphatase activity.
  
  
 
0.905
Ste:CG33241
Protein kinase regulator activity. It is involved in the biological process described with: regulation of protein serine/threonine phosphatase activity.
  
  
 
0.905
Ste:CG33243
Stellate protein CG33243; Unknown. In males lacking the Y chromosome, its strong overexpression leads to the appearance of proteinaceous star-shaped crystals in the primary spermatocytes causing meiotic drive, possibly by interfering with normal casein kinase 2 activity.
  
  
 
0.905
Ste:CG33244
Protein kinase regulator activity. It is involved in the biological process described with: regulation of protein serine/threonine phosphatase activity.
  
  
 
0.905
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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