| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Atac3 | Ets96B | FBpp0301175 | FBpp0089401 | Ada2a-containing complex component 3 (Atac3) encodes a protein involved in chromatin remodeling and histone acetylation. | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | 0.560 |
| CaBP1 | Ets96B | FBpp0311643 | FBpp0089401 | Protein disulfide-isomerase A6 homolog; Calcium-binding protein 1 (CaBP1) encodes a protein that resides in the lumen of the endoplasmic reticulum. It seems to be relocated outside cells during apoptosis and involved in the phagocytosis of apoptotic cells. | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | 0.493 |
| Ets96B | Atac3 | FBpp0089401 | FBpp0301175 | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | Ada2a-containing complex component 3 (Atac3) encodes a protein involved in chromatin remodeling and histone acetylation. | 0.560 |
| Ets96B | CaBP1 | FBpp0089401 | FBpp0311643 | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | Protein disulfide-isomerase A6 homolog; Calcium-binding protein 1 (CaBP1) encodes a protein that resides in the lumen of the endoplasmic reticulum. It seems to be relocated outside cells during apoptosis and involved in the phagocytosis of apoptotic cells. | 0.493 |
| Ets96B | Poxn | FBpp0089401 | FBpp0302942 | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | Paired box pox-neuro protein; Pox neuro (Poxn) encodes a transcriptional factor that specifies the differences between mono-innervated external sensory (m-es) organs and poly-innervated external sensory (p-es) organs. Poxn expression in the external sensory organ precursor determines the fate to form larval p-es organs and adult chemosensory bristles. | 0.541 |
| Ets96B | SK | FBpp0089401 | FBpp0310909 | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | Small conductance calcium-activated potassium channel protein; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin (By similarity). | 0.746 |
| Ets96B | Sulf1 | FBpp0089401 | FBpp0306754 | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | Extracellular sulfatase SULF-1 homolog; Sulfated (Sulf1) encodes a heparan sulfate modifying enzyme, which extracellularly removes specific 6-O-sulfate groups from heparan sulfate in a post-synthetic manner. It regulates Wg signaling by reducing extracellular wg protein levels. It also regulates Hh signaling by acting as a positive regulator in cells producing the product of hh and a negative regulator in cells receiving the product of hh. | 0.485 |
| Ets96B | abo | FBpp0089401 | FBpp0079757 | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | Abnormal oocyte (abo) encodes a negative regulator of histone transcription genes by its binding to their regulatory regions. abo mutations cause a maternal-effect lethality that can be rescued by specific regions of heterochromatin during early embryogenesis. | 0.642 |
| Ets96B | disco-r | FBpp0089401 | FBpp0301985 | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | Disco-related, isoform A; Disco-related (disco-r) encodes a C2H2 zinc-finger transcription factor. It has known roles in larval and adult appendage development, where it appears to control proximal-distal fate in ventral appendages including adult legs, antenna, and larval and adult mouthparts. | 0.493 |
| Ets96B | ppk9 | FBpp0089401 | FBpp0111506 | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | Pickpocket 9, isoform A; Sodium channel activity. It is involved in the biological process described with: sodium ion transport; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. | 0.441 |
| Ets96B | sv | FBpp0089401 | FBpp0088366 | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | Shaven, isoform A; Shaven (sv) encodes a transcription factor and a member of the paired box family of genes. It is primarily involved in the terminal differentiation of specific cell types during the development of a variety of sensory organs, including the bristles and the eye. | 0.502 |
| Ets96B | tai | FBpp0089401 | FBpp0293513 | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | Taiman, isoform G; Taiman (tai) encodes an ecdysone receptor co-activator related to mammalian steroid receptor coactivator (SRC) proteins. It contributes to border cell migration. | 0.909 |
| Poxn | Ets96B | FBpp0302942 | FBpp0089401 | Paired box pox-neuro protein; Pox neuro (Poxn) encodes a transcriptional factor that specifies the differences between mono-innervated external sensory (m-es) organs and poly-innervated external sensory (p-es) organs. Poxn expression in the external sensory organ precursor determines the fate to form larval p-es organs and adult chemosensory bristles. | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | 0.541 |
| Poxn | sv | FBpp0302942 | FBpp0088366 | Paired box pox-neuro protein; Pox neuro (Poxn) encodes a transcriptional factor that specifies the differences between mono-innervated external sensory (m-es) organs and poly-innervated external sensory (p-es) organs. Poxn expression in the external sensory organ precursor determines the fate to form larval p-es organs and adult chemosensory bristles. | Shaven, isoform A; Shaven (sv) encodes a transcription factor and a member of the paired box family of genes. It is primarily involved in the terminal differentiation of specific cell types during the development of a variety of sensory organs, including the bristles and the eye. | 0.404 |
| SK | Ets96B | FBpp0310909 | FBpp0089401 | Small conductance calcium-activated potassium channel protein; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin (By similarity). | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | 0.746 |
| Sulf1 | Ets96B | FBpp0306754 | FBpp0089401 | Extracellular sulfatase SULF-1 homolog; Sulfated (Sulf1) encodes a heparan sulfate modifying enzyme, which extracellularly removes specific 6-O-sulfate groups from heparan sulfate in a post-synthetic manner. It regulates Wg signaling by reducing extracellular wg protein levels. It also regulates Hh signaling by acting as a positive regulator in cells producing the product of hh and a negative regulator in cells receiving the product of hh. | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | 0.485 |
| abo | Ets96B | FBpp0079757 | FBpp0089401 | Abnormal oocyte (abo) encodes a negative regulator of histone transcription genes by its binding to their regulatory regions. abo mutations cause a maternal-effect lethality that can be rescued by specific regions of heterochromatin during early embryogenesis. | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | 0.642 |
| disco-r | Ets96B | FBpp0301985 | FBpp0089401 | Disco-related, isoform A; Disco-related (disco-r) encodes a C2H2 zinc-finger transcription factor. It has known roles in larval and adult appendage development, where it appears to control proximal-distal fate in ventral appendages including adult legs, antenna, and larval and adult mouthparts. | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | 0.493 |
| ppk9 | Ets96B | FBpp0111506 | FBpp0089401 | Pickpocket 9, isoform A; Sodium channel activity. It is involved in the biological process described with: sodium ion transport; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | 0.441 |
| sv | Ets96B | FBpp0088366 | FBpp0089401 | Shaven, isoform A; Shaven (sv) encodes a transcription factor and a member of the paired box family of genes. It is primarily involved in the terminal differentiation of specific cell types during the development of a variety of sensory organs, including the bristles and the eye. | ETV5-related protein Ets96B; Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60. | 0.502 |