STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Indy-2Protein I'm not dead yet 2; Cation-independent electroneutral transporter (not associated with membrane depolarization) of a variety of tricarboxylic and dicarboxylic acid-cycle intermediates. There is also small, but detectable, transport of monocarboxylics. Transport is through the epithelium of the gut and across the plasma membranes of organs involved in intermediary metabolism and storage (By similarity). Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. (562 aa)    
Predicted Functional Partners:
mthl12
Probable G-protein coupled receptor Mth-like 12; G protein-coupled receptor activity. It is involved in the biological process described with: determination of adult lifespan; cell surface receptor signaling pathway; G protein-coupled receptor signaling pathway; response to starvation.
      
 0.607
mthl6
Probable G-protein coupled receptor Mth-like 6; G protein-coupled receptor activity. It is involved in the biological process described with: G protein-coupled receptor signaling pathway; response to starvation; cell surface receptor signaling pathway; determination of adult lifespan.
      
 0.606
mthl2
Probable G-protein coupled receptor Mth-like 2; G protein-coupled receptor activity. It is involved in the biological process described with: cell surface receptor signaling pathway; G protein-coupled receptor signaling pathway; response to starvation; determination of adult lifespan.
      
 0.547
mthl7
Probable G-protein coupled receptor Mth-like 7; G protein-coupled receptor activity. It is involved in the biological process described with: determination of adult lifespan; cell surface receptor signaling pathway; G protein-coupled receptor signaling pathway; response to starvation; Belongs to the G-protein coupled receptor 2 family. Mth subfamily.
      
 0.533
CG7309
Uncharacterized protein; Citrate transmembrane transporter activity; succinate transmembrane transporter activity. It is involved in the biological process described with: citrate transport; sodium ion transport; anion transmembrane transport.
  
  
0.497
mthl3
Probable G-protein coupled receptor Mth-like 3; G protein-coupled receptor activity. It is involved in the biological process described with: determination of adult lifespan; cell surface receptor signaling pathway; G protein-coupled receptor signaling pathway; response to starvation.
      
 0.497
Cdk5alpha
Cdk5 activator-like protein (Cdk5alpha) encodes the sole, essential stimulatory subunit for the kinase encoded by Cdk5. The Cdk5/Cdk5alpha complex is active in post-mitotic neurons. It is required for synaptic homeostasis and fidelity of axon patterning, and altered activity causes adult-onset neurodegeneration.
      
 0.495
Acp62F
Accessory gland protein Acp62F; Responsible for physiological and behavioral changes in mated female flies. May contribute to the toxicity of seminal fluid and the decreased life-span of mated females. May also affect neuromuscular events after mating concerning sperm storage and egg release.
   
  
 0.468
Cbs
Cystathionine beta-synthase (Cbs) encodes an enzyme involved in endoplasmic reticulum stress response; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
  
 0.464
CG11226
AT16729p.
   
  
 0.458
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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