STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MutedBiogenesis of lysosome-related organelles complex 1 subunit 5; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis. Belongs to the BLOC1S5 family. (160 aa)    
Predicted Functional Partners:
Pldn
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis and membrane trafficking in synapses. In response to high synaptic activity at neuromuscular junctions, plays a key role in promoting efficient synaptic vesicle recycling and re-formation through early endosomes.
    
 0.988
Dysb
Dysbindin protein homolog; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis and membrane trafficking in synapses. In response to high synaptic activity at neuromuscular junctions, stabilizes Pldn protein levels and, together with Pldn, plays a role in promoting efficient synaptic vesicle recycling and re-formation through early endosomes ; Belongs to the dysbindin family.
    
 0.955
Blos1
Biogenesis of lysosome-related organelles complex 1 subunit 1; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis and membrane trafficking in synapses. In response to high synaptic activity at neuromuscular junctions, stabilizes Pldn protein levels and, together with Pldn, plays a role in promoting efficient synaptic vesicle recycling and re-formation through early endosomes.
   
 0.939
CG7071
RE40914p; It is involved in the biological process described with: vacuolar proton-transporting V-type ATPase complex assembly.
      
 0.913
Snapin
SNAPIN protein homolog; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis. May participate in the coupling of lysosomes to microtubule plus-end-directed kinesin motor (By similarity).
   
 0.896
CG14562
Uncharacterized protein, isoform A; It is involved in the biological process described with: organelle organization.
     
 0.891
Blos2
Biogenesis of lysosome-related organelles complex 1 subunit 2; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis. Belongs to the BLOC1S2 family.
    
 0.883
Blos4
Biogenesis of lysosome-related organelles complex 1 subunit 4; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis. Belongs to the BLOC1S4 family.
    
 0.882
Vha26
V-type proton ATPase subunit E; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
      
 0.838
CG6865
Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
      
 0.835
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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