STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FiliFish-lips, isoform C; Fish-lips (Fili) encodes a leucine-rich repeat family transmembrane protein. It regulates autonomous and nonautonomous apoptosis caused by the dioxin receptor homolog encoded by ss. (738 aa)    
Predicted Functional Partners:
CG12708
LD21346p.
      
 0.670
Cirl
Latrophilin Cirl; Latrotoxin receptor activity; G protein-coupled receptor activity; carbohydrate binding; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
   
 
 0.655
CG14567
Uncharacterized protein.
    
 
 0.610
CG13532
RE31221p.
      
 0.607
CG15803
Uncharacterized protein, isoform C; Protein C-terminus binding.
    
 
 0.607
TwdlC
TweedleC; Structural constituent of chitin-based cuticle. It is involved in the biological process described with: chitin-based cuticle development.
      
 0.604
CG13321
RE03883p.
      
 0.601
Lap1
Protein lap1; May have a role in assembling adherens junctions.
  
   
 0.538
CG42594
Uncharacterized protein, isoform C; Potassium channel activity; potassium ion leak channel activity. It is involved in the biological process described with: stabilization of membrane potential; potassium ion transmembrane transport; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
  
 0.532
CG3040
GM01152p.
  
   
 0.531
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.