node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fas2 | Fas3 | FBpp0310127 | FBpp0111717 | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | 0.832 |
Fas2 | Gal | FBpp0310127 | FBpp0078861 | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | Beta galactosidase (Gal) encodes a putative digestive enzyme that hydrolyses beta-galactosides into monosaccharides. Gal is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the glycosyl hydrolase 35 family. | 0.627 |
Fas2 | Nrg | FBpp0310127 | FBpp0297081 | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | Neuroglian; The long isoform may play a role in neural and glial cell adhesion in the developing embryo. The short isoform may be a more general cell adhesion molecule involved in other tissues and imaginal disk morphogenesis. Vital for embryonic development. Essential for septate junctions. Septate junctions, which are the equivalent of vertebrates tight junctions, are characterized by regular arrays of transverse structures that span the intermembrane space and form a physical barrier to diffusion. Required for the blood-brain barrier formation. | 0.813 |
Fas2 | Nrx-IV | FBpp0310127 | FBpp0075730 | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | Neurexin-4; Seems to play a role in the formation and function of septate junctions. Septate junctions, which are the equivalent of vertebrates tight junctions, are characterized by regular arrays of transverse structures that span the intermembrane space and form a physical barrier to diffusion. Required for the blood-brain barrier formation. Belongs to the neurexin family. | 0.541 |
Fas2 | shg | FBpp0310127 | FBpp0071475 | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | DE-cadherin; Cadherins are calcium-dependent cell adhesion proteins. In connecting cells they preferentially interact with themselves in a homophilic manner; cadherins may thus contribute to the sorting of heterogeneous cell types. During oogenesis, integral component of the guidance mechanisms that regulate the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Functions downstream of the two chemoattractant receptors, Pvr and Egfr, to promote BC adhesion between the leader cells of the migrating cluster and the surroundi [...] | 0.521 |
Fas3 | Fas2 | FBpp0111717 | FBpp0310127 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | 0.832 |
Fas3 | Gal | FBpp0111717 | FBpp0078861 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | Beta galactosidase (Gal) encodes a putative digestive enzyme that hydrolyses beta-galactosides into monosaccharides. Gal is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the glycosyl hydrolase 35 family. | 0.680 |
Fas3 | Lac | FBpp0111717 | FBpp0087044 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | Lachesin (Lac) encodes a cell surface protein that belongs to the Ig superfamily. It is required for the proper ultrastructural organisation of septate junctions. Lac is required for tracheal system morphogenesis and for muscle contractions associated with peristalsis. | 0.735 |
Fas3 | Nrg | FBpp0111717 | FBpp0297081 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | Neuroglian; The long isoform may play a role in neural and glial cell adhesion in the developing embryo. The short isoform may be a more general cell adhesion molecule involved in other tissues and imaginal disk morphogenesis. Vital for embryonic development. Essential for septate junctions. Septate junctions, which are the equivalent of vertebrates tight junctions, are characterized by regular arrays of transverse structures that span the intermembrane space and form a physical barrier to diffusion. Required for the blood-brain barrier formation. | 0.862 |
Fas3 | Nrx-IV | FBpp0111717 | FBpp0075730 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | Neurexin-4; Seems to play a role in the formation and function of septate junctions. Septate junctions, which are the equivalent of vertebrates tight junctions, are characterized by regular arrays of transverse structures that span the intermembrane space and form a physical barrier to diffusion. Required for the blood-brain barrier formation. Belongs to the neurexin family. | 0.792 |
Fas3 | Stat92E | FBpp0111717 | FBpp0306651 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | Signal-transducer and activator of transcription protein at 92E (Stat92E) encodes a transcription factor that shuttles between the cytosol and nucleus and functions in the JAK/STAT pathway. Its roles include proliferation, growth control, organismal metabolism, cell competition, stem cell self-renewal, immunity and developmental patterning. | 0.665 |
Fas3 | crb | FBpp0111717 | FBpp0293268 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | Protein crumbs; Plays a central role in cell polarity establishment. Participates in the assembly, positioning and maintenance of adherens junctions via its interaction with the SAC complex. Controls the coalescence of the spots of zonula adherens (ZA) into a adhesive ring around the cells. It may act as a signal. Involved in morphogenesis of the photoreceptor rhabdomere, for positioning and growth of rhabdomere and AJ during the crucial period of photoreceptor extension along the proximodistal axis of the retina. Component of the crb-galla-Xpd (CGX) complex which is essential for prop [...] | 0.701 |
Fas3 | eya | FBpp0111717 | FBpp0078964 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | Developmental protein eyes absent; Tyrosine phosphatase thought to play a role in transcription regulation during organogenesis through its intrinsic protein phosphatase activity. The phosphatase activity was shown in vitro. Appears to function together with So and Dac in eye development. Required for the survival of eye progenitor cells at a critical stage in morphogenesis. Belongs to the HAD-like hydrolase superfamily. EYA family. | 0.842 |
Fas3 | shg | FBpp0111717 | FBpp0071475 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | DE-cadherin; Cadherins are calcium-dependent cell adhesion proteins. In connecting cells they preferentially interact with themselves in a homophilic manner; cadherins may thus contribute to the sorting of heterogeneous cell types. During oogenesis, integral component of the guidance mechanisms that regulate the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Functions downstream of the two chemoattractant receptors, Pvr and Egfr, to promote BC adhesion between the leader cells of the migrating cluster and the surroundi [...] | 0.878 |
Fas3 | zfh1 | FBpp0111717 | FBpp0303607 | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | Zinc finger protein 1; Involved in the development of the embryonic central nervous system, embryonic mesoderm and adult musculature. Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family. | 0.838 |
Gal | Fas2 | FBpp0078861 | FBpp0310127 | Beta galactosidase (Gal) encodes a putative digestive enzyme that hydrolyses beta-galactosides into monosaccharides. Gal is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the glycosyl hydrolase 35 family. | Fasciclin-2; Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles. | 0.627 |
Gal | Fas3 | FBpp0078861 | FBpp0111717 | Beta galactosidase (Gal) encodes a putative digestive enzyme that hydrolyses beta-galactosides into monosaccharides. Gal is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the glycosyl hydrolase 35 family. | Fasciclin-3; Mediates cell adhesion in a Ca(2+)-independent manner. It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system. | 0.680 |
Gal | Stat92E | FBpp0078861 | FBpp0306651 | Beta galactosidase (Gal) encodes a putative digestive enzyme that hydrolyses beta-galactosides into monosaccharides. Gal is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the glycosyl hydrolase 35 family. | Signal-transducer and activator of transcription protein at 92E (Stat92E) encodes a transcription factor that shuttles between the cytosol and nucleus and functions in the JAK/STAT pathway. Its roles include proliferation, growth control, organismal metabolism, cell competition, stem cell self-renewal, immunity and developmental patterning. | 0.549 |
Gal | crb | FBpp0078861 | FBpp0293268 | Beta galactosidase (Gal) encodes a putative digestive enzyme that hydrolyses beta-galactosides into monosaccharides. Gal is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the glycosyl hydrolase 35 family. | Protein crumbs; Plays a central role in cell polarity establishment. Participates in the assembly, positioning and maintenance of adherens junctions via its interaction with the SAC complex. Controls the coalescence of the spots of zonula adherens (ZA) into a adhesive ring around the cells. It may act as a signal. Involved in morphogenesis of the photoreceptor rhabdomere, for positioning and growth of rhabdomere and AJ during the crucial period of photoreceptor extension along the proximodistal axis of the retina. Component of the crb-galla-Xpd (CGX) complex which is essential for prop [...] | 0.534 |
Gal | eya | FBpp0078861 | FBpp0078964 | Beta galactosidase (Gal) encodes a putative digestive enzyme that hydrolyses beta-galactosides into monosaccharides. Gal is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the glycosyl hydrolase 35 family. | Developmental protein eyes absent; Tyrosine phosphatase thought to play a role in transcription regulation during organogenesis through its intrinsic protein phosphatase activity. The phosphatase activity was shown in vitro. Appears to function together with So and Dac in eye development. Required for the survival of eye progenitor cells at a critical stage in morphogenesis. Belongs to the HAD-like hydrolase superfamily. EYA family. | 0.604 |