STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG15019GEO12024p1; Basal RNA polymerase II transcription machinery binding. It is involved in the biological process described with: dendrite extension. (146 aa)    
Predicted Functional Partners:
RpL30
Ribosomal protein L30, isoform B; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation.
   
   0.799
CG3224
Zinc finger protein 593 homolog; Nucleic acid binding; zinc ion binding; ribosomal large subunit binding. It is involved in the biological process described with: ribosomal large subunit export from nucleus; Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.
   
 
 0.776
CG11563
MIP13505p1; RNA binding. It is involved in the biological process described with: ribosomal large subunit biogenesis.
   
    0.771
NHP2
H/ACA ribonucleoprotein complex subunit 2-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
   
   0.761
RpL14
Ribosomal protein L14 (RpL14) encodes a component of the large subunit of cytoplasmic ribosomes, which translate mRNAs encoded by the nuclear genome. RpL14 is haploinsufficient - heterozygous mutants display the 'Minute' phenotype, characterized by a slower developmental rate and small adult bristles.
   
   0.735
RpL11
60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
   
   0.728
CG15535
GEO10831p1.
   
    0.703
RpL37A
60S ribosomal protein L37a; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation; Belongs to the eukaryotic ribosomal protein eL43 family.
   
   0.698
RpL24-like
Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of NOG1 to pre-60S particles (By similarity).
   
   0.693
RpL7A
Ribosomal protein L7A (RpL7A) encodes a ribosomal structural constituent; Belongs to the eukaryotic ribosomal protein eL8 family.
   
   0.692
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.