| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG10694 | CG12061 | FBpp0083927 | FBpp0304871 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | Uncharacterized protein, isoform D; Calcium, potassium:sodium antiporter activity; calcium channel activity. It is involved in the biological process described with: calcium ion transmembrane transport; cellular calcium ion homeostasis; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.459 |
| CG10694 | CG1598 | FBpp0083927 | FBpp0088029 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | 0.806 |
| CG10694 | CG17167 | FBpp0083927 | FBpp0290031 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | RE48874p; Calcium, potassium:sodium antiporter activity; calcium channel activity. It is involved in the biological process described with: calcium ion transmembrane transport; cellular calcium ion homeostasis; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.441 |
| CG10694 | CG7215 | FBpp0083927 | FBpp0099676 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | RE23139p1. | 0.626 |
| CG10694 | CG9853 | FBpp0083927 | FBpp0112104 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | Golgi to ER traffic protein 4 homolog; May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane. | 0.808 |
| CG10694 | Nckx30C | FBpp0083927 | FBpp0292911 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | Sodium/potassium/calcium exchanger Nckx30C; May function in the removal and maintenance of calcium homeostasis during signaling in the adult and in signaling events during embryogenesis and patterning of imaginal disks. Transports one Ca(2+) and 1 K(+) in exchange for 4 Na(+). Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily. | 0.441 |
| CG10694 | Rad23 | FBpp0083927 | FBpp0305835 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | 0.923 |
| CG10694 | Sgt | FBpp0083927 | FBpp0296963 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | Small glutamine-rich tetratricopeptide containing protein (Sgt) encodes a protein involved in the regulation of the protein folding mediated by chaperones. | 0.829 |
| CG10694 | zyd | FBpp0083927 | FBpp0290356 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | Zydeco, isoform F; Zydeco (zyd) encodes a potassium-dependent sodium/calcium exchanger found in cortex glia. It is thought to serve as a key calcium export pathway to control calcium oscillations that occur in membrane microdomains of the glial cell; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.441 |
| CG12061 | CG10694 | FBpp0304871 | FBpp0083927 | Uncharacterized protein, isoform D; Calcium, potassium:sodium antiporter activity; calcium channel activity. It is involved in the biological process described with: calcium ion transmembrane transport; cellular calcium ion homeostasis; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | 0.459 |
| CG12061 | CG17167 | FBpp0304871 | FBpp0290031 | Uncharacterized protein, isoform D; Calcium, potassium:sodium antiporter activity; calcium channel activity. It is involved in the biological process described with: calcium ion transmembrane transport; cellular calcium ion homeostasis; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | RE48874p; Calcium, potassium:sodium antiporter activity; calcium channel activity. It is involved in the biological process described with: calcium ion transmembrane transport; cellular calcium ion homeostasis; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.470 |
| CG12061 | CG9853 | FBpp0304871 | FBpp0112104 | Uncharacterized protein, isoform D; Calcium, potassium:sodium antiporter activity; calcium channel activity. It is involved in the biological process described with: calcium ion transmembrane transport; cellular calcium ion homeostasis; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | Golgi to ER traffic protein 4 homolog; May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane. | 0.729 |
| CG12061 | Nckx30C | FBpp0304871 | FBpp0292911 | Uncharacterized protein, isoform D; Calcium, potassium:sodium antiporter activity; calcium channel activity. It is involved in the biological process described with: calcium ion transmembrane transport; cellular calcium ion homeostasis; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | Sodium/potassium/calcium exchanger Nckx30C; May function in the removal and maintenance of calcium homeostasis during signaling in the adult and in signaling events during embryogenesis and patterning of imaginal disks. Transports one Ca(2+) and 1 K(+) in exchange for 4 Na(+). Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily. | 0.457 |
| CG12061 | Rad23 | FBpp0304871 | FBpp0305835 | Uncharacterized protein, isoform D; Calcium, potassium:sodium antiporter activity; calcium channel activity. It is involved in the biological process described with: calcium ion transmembrane transport; cellular calcium ion homeostasis; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | 0.441 |
| CG12061 | zyd | FBpp0304871 | FBpp0290356 | Uncharacterized protein, isoform D; Calcium, potassium:sodium antiporter activity; calcium channel activity. It is involved in the biological process described with: calcium ion transmembrane transport; cellular calcium ion homeostasis; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | Zydeco, isoform F; Zydeco (zyd) encodes a potassium-dependent sodium/calcium exchanger found in cortex glia. It is thought to serve as a key calcium export pathway to control calcium oscillations that occur in membrane microdomains of the glial cell; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.436 |
| CG1598 | CG10694 | FBpp0088029 | FBpp0083927 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | 0.806 |
| CG1598 | CG7215 | FBpp0088029 | FBpp0099676 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | RE23139p1. | 0.683 |
| CG1598 | CG7546 | FBpp0088029 | FBpp0288465 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | Uncharacterized protein, isoform D; Enzyme binding; misfolded protein binding; polyubiquitin modification-dependent protein binding. It is involved in the biological process described with: negative regulation of apoptotic process; ubiquitin-dependent ERAD pathway. | 0.760 |
| CG1598 | CG9853 | FBpp0088029 | FBpp0112104 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | Golgi to ER traffic protein 4 homolog; May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane. | 0.993 |
| CG1598 | Rad23 | FBpp0088029 | FBpp0305835 | ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | 0.807 |