STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG17691Uncharacterized protein, isoform C; Alpha-ketoacid dehydrogenase activity. It is involved in the biological process described with: response to nutrient; fatty-acyl-CoA biosynthetic process; branched-chain amino acid catabolic process. (364 aa)    
Predicted Functional Partners:
CG8199
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
CG5599
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Acetyltransferase activity; lipoic acid binding.
 0.998
CG7430
Flavin adenine dinucleotide binding; dihydrolipoyl dehydrogenase activity; electron transfer activity. It is involved in the biological process described with: tricarboxylic acid cycle; lipoamide metabolic process; oxidation-reduction process; glycine catabolic process; cell redox homeostasis.
 
 0.994
Pdha
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.987
CG7024
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.986
CG5214
GM01350p; Dihydrolipoyllysine-residue succinyltransferase activity. It is involved in the biological process described with: cellular respiration; tricarboxylic acid cycle.
 
 0.974
muc
Midline uncoordinated, isoform B; Pyruvate dehydrogenase (NAD+) activity; dihydrolipoyllysine-residue acetyltransferase activity. It is involved in the biological process described with: grooming behavior; acetyl-CoA biosynthetic process from pyruvate.
 0.973
CG1673
Branched-chain-amino-acid transaminase activity. It is involved in the biological process described with: valine biosynthetic process; branched-chain amino acid biosynthetic process; leucine biosynthetic process; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.960
Ldh
Lactate dehydrogenase (Ldh) encodes a protein involved in myoblast fusion and somatic muscle development; Belongs to the LDH/MDH superfamily. LDH family.
  
 0.921
CG13334
Uncharacterized protein, isoform A; L-lactate dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process; carbohydrate metabolic process; carboxylic acid metabolic process; Belongs to the LDH/MDH superfamily.
  
 0.920
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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