STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp4aa1Probable cytochrome P450 4aa1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides; Belongs to the cytochrome P450 family. (510 aa)    
Predicted Functional Partners:
CG42329
NRF domain-containing protein; Transferase activity, transferring acyl groups other than amino-acyl groups.
   
    0.564
glob2
Globin 2, isoform B; Oxygen binding; heme binding; Belongs to the globin family.
   
  
 0.533
Ir7g
Ionotropic receptor 7g.
   
  
 0.516
Ir7f
Ionotropic receptor 7f; Ligand-gated ion channel activity. It is involved in the biological process described with: detection of chemical stimulus.
   
  
 0.499
GstE10
Glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process; Belongs to the GST superfamily.
      
 0.495
Cpr65Ec
Cuticular protein 65Ec; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development.
      
 0.491
alpha-Est10
Carboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family.
      
 0.491
Cyp303a1
Probable cytochrome P450 303a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.460
CG6012
MIP25013p; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.454
Cyp6t1
Probable cytochrome P450 6t1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.435
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.