STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GscHomeobox protein goosecoid; Appears to regulate regional development of specific tissues. Can rescue axis polarity in UV-radiated Xenopus embryos (485 aa)    
Predicted Functional Partners:
CG17829
Uncharacterized protein, isoform A; Metal ion binding; nucleic acid binding
   
   0.989
su(s)
Protein suppressor of sable; Affects the transcript levels of those alleles that it suppresses. May be involved in influencing complex assembly on cryptic 5'-splice sites or nuclear RNA export; binds RNA preferentially at a sequence that resembles a cryptic 5'-splice site (in vitro)
   
   0.989
TrxT
Thioredoxin-T; Probably participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Its tissue specificity suggests a regulatory role in the germline
    
   0.989
Spt6
Transcription elongation factor SPT6; Transcription elongation factor which binds histone H3 and enhances transcription elongation by RNA polymerase II (RNAPII). Required for the transcriptional induction of heat shock response genes and for maximal recruitment of two other elongation factors, Spt5 and Paf1, to the induced Hsp70. Plays a critical role in normal fly development throughout the lifecycle
    
   0.989
TAF1C-like
TATA box-binding protein-associated factor RNA polymerase I subunit C-like; It is involved in the biological process described with: positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
    
   0.989
CG3217
CKII-alpha subunit interactor-3
    
   0.989
hale
Hale-bopp
    
   0.989
CTPsyn
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides (By similarity). Isoform 1 is required for cytoophidium assembly in female germline cells
    
   0.989
CG7611
WD repeat-containing protein 26 homolog; G-beta-like protein involved in cell signal transduction (By similarity)
    
   0.989
CG14655
GH23506p; Metal ion binding; nucleic acid binding
    
   0.989
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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