node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arf51F | Ehbp1 | FBpp0086507 | FBpp0113119 | ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). Promotes cell movement and remodeling of the actin cytoskeleton during compound eye morphogenesis. Required for normal ethanol-induced tolerance and preference. Probably after Efa6-mediated activation, counteracts ethanol-induced sedation. | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | 0.669 |
Arf51F | Eps-15 | FBpp0086507 | FBpp0072340 | ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). Promotes cell movement and remodeling of the actin cytoskeleton during compound eye morphogenesis. Required for normal ethanol-induced tolerance and preference. Probably after Efa6-mediated activation, counteracts ethanol-induced sedation. | Epidermal growth factor receptor pathway substrate clone 15 (Eps-15) encodes a multi-domain adaptor protein involved in endocytosis. It interacts with several other endocytic factors such as those encoded by shi, stnB, Dap160 and AP-2alpha. It is enriched at sites of endocytosis and is required for normal synaptic bouton development and vesicle endocytosis during high frequency stimulation. | 0.578 |
Arf51F | Past1 | FBpp0086507 | FBpp0082123 | ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). Promotes cell movement and remodeling of the actin cytoskeleton during compound eye morphogenesis. Required for normal ethanol-induced tolerance and preference. Probably after Efa6-mediated activation, counteracts ethanol-induced sedation. | Putative Achaete Scute Target 1 (Past1) encodes a protein that associates predominantly with the plasma membrane and genetically interacts with N. It contributes to endocytosis, male sterility, temperature sensitivity, life span and differentiation of photoreceptors R1/R6/R7 and cone cells; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.756 |
Arf51F | Rab11 | FBpp0086507 | FBpp0083413 | ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). Promotes cell movement and remodeling of the actin cytoskeleton during compound eye morphogenesis. Required for normal ethanol-induced tolerance and preference. Probably after Efa6-mediated activation, counteracts ethanol-induced sedation. | Rab11, isoform A; Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. | 0.933 |
Arf51F | Sec15 | FBpp0086507 | FBpp0083436 | ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). Promotes cell movement and remodeling of the actin cytoskeleton during compound eye morphogenesis. Required for normal ethanol-induced tolerance and preference. Probably after Efa6-mediated activation, counteracts ethanol-induced sedation. | Exocyst complex component 6; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | 0.569 |
CG6805 | Ehbp1 | FBpp0086120 | FBpp0113119 | LD06095p; Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. It is involved in the biological process described with: positive regulation of flagellated sperm motility; phosphatidylinositol dephosphorylation; inositol phosphate dephosphorylation. | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | 0.811 |
Ehbp1 | Arf51F | FBpp0113119 | FBpp0086507 | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). Promotes cell movement and remodeling of the actin cytoskeleton during compound eye morphogenesis. Required for normal ethanol-induced tolerance and preference. Probably after Efa6-mediated activation, counteracts ethanol-induced sedation. | 0.669 |
Ehbp1 | CG6805 | FBpp0113119 | FBpp0086120 | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | LD06095p; Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. It is involved in the biological process described with: positive regulation of flagellated sperm motility; phosphatidylinositol dephosphorylation; inositol phosphate dephosphorylation. | 0.811 |
Ehbp1 | Eps-15 | FBpp0113119 | FBpp0072340 | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | Epidermal growth factor receptor pathway substrate clone 15 (Eps-15) encodes a multi-domain adaptor protein involved in endocytosis. It interacts with several other endocytic factors such as those encoded by shi, stnB, Dap160 and AP-2alpha. It is enriched at sites of endocytosis and is required for normal synaptic bouton development and vesicle endocytosis during high frequency stimulation. | 0.647 |
Ehbp1 | Mical | FBpp0113119 | FBpp0297564 | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | [F-actin]-monooxygenase Mical; Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits at 'Met-44' and 'Met-47' through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament disassembly and prevent repolymerization. Plays a key role in semaphorin-plexin repulsive axon guidance and cell morphological changes, probably via its ability to modify and regulate actin. Belongs to the Mical family. | 0.629 |
Ehbp1 | Past1 | FBpp0113119 | FBpp0082123 | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | Putative Achaete Scute Target 1 (Past1) encodes a protein that associates predominantly with the plasma membrane and genetically interacts with N. It contributes to endocytosis, male sterility, temperature sensitivity, life span and differentiation of photoreceptors R1/R6/R7 and cone cells; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.811 |
Ehbp1 | Rab10 | FBpp0113119 | FBpp0077029 | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | LD39986p; Rab10 (Rab10) encodes a small GTPase that contributes to vesicle trafficking regulation. It is involved in basement membrane organization. | 0.926 |
Ehbp1 | Rab11 | FBpp0113119 | FBpp0083413 | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | Rab11, isoform A; Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. | 0.737 |
Ehbp1 | Rab8 | FBpp0113119 | FBpp0074690 | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | Rab8, isoform A; Rab8 (Rab8) encodes a member of the Rab GTPase family that regulates the function of the recycling endosome, where it localizes. | 0.799 |
Ehbp1 | Sec15 | FBpp0113119 | FBpp0083436 | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | Exocyst complex component 6; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | 0.756 |
Ehbp1 | Zasp52 | FBpp0113119 | FBpp0099801 | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | Z band alternatively spliced PDZ-motif protein 52 (Zasp52) encodes a member of the Zasp protein family. It is a scaffold protein that binds the product of Actn and localizes to muscle attachment sites and Z-discs in muscle cells, as well as localizing cortically in non-muscle cells. It plays a role in muscle development, especially in myofibril assembly. | 0.647 |
Eps-15 | Arf51F | FBpp0072340 | FBpp0086507 | Epidermal growth factor receptor pathway substrate clone 15 (Eps-15) encodes a multi-domain adaptor protein involved in endocytosis. It interacts with several other endocytic factors such as those encoded by shi, stnB, Dap160 and AP-2alpha. It is enriched at sites of endocytosis and is required for normal synaptic bouton development and vesicle endocytosis during high frequency stimulation. | ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). Promotes cell movement and remodeling of the actin cytoskeleton during compound eye morphogenesis. Required for normal ethanol-induced tolerance and preference. Probably after Efa6-mediated activation, counteracts ethanol-induced sedation. | 0.578 |
Eps-15 | Ehbp1 | FBpp0072340 | FBpp0113119 | Epidermal growth factor receptor pathway substrate clone 15 (Eps-15) encodes a multi-domain adaptor protein involved in endocytosis. It interacts with several other endocytic factors such as those encoded by shi, stnB, Dap160 and AP-2alpha. It is enriched at sites of endocytosis and is required for normal synaptic bouton development and vesicle endocytosis during high frequency stimulation. | Eps15 homology domain containing protein-binding protein 1 (Ehbp1) encodes a protein that mediates asymmetric protein secretion. It regulates the trafficking and secretion of distinct Notch signaling components and extracellular membrane proteins. | 0.647 |
Eps-15 | Past1 | FBpp0072340 | FBpp0082123 | Epidermal growth factor receptor pathway substrate clone 15 (Eps-15) encodes a multi-domain adaptor protein involved in endocytosis. It interacts with several other endocytic factors such as those encoded by shi, stnB, Dap160 and AP-2alpha. It is enriched at sites of endocytosis and is required for normal synaptic bouton development and vesicle endocytosis during high frequency stimulation. | Putative Achaete Scute Target 1 (Past1) encodes a protein that associates predominantly with the plasma membrane and genetically interacts with N. It contributes to endocytosis, male sterility, temperature sensitivity, life span and differentiation of photoreceptors R1/R6/R7 and cone cells; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.506 |
Eps-15 | Rab11 | FBpp0072340 | FBpp0083413 | Epidermal growth factor receptor pathway substrate clone 15 (Eps-15) encodes a multi-domain adaptor protein involved in endocytosis. It interacts with several other endocytic factors such as those encoded by shi, stnB, Dap160 and AP-2alpha. It is enriched at sites of endocytosis and is required for normal synaptic bouton development and vesicle endocytosis during high frequency stimulation. | Rab11, isoform A; Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. | 0.565 |