node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ank | Ank2 | FBpp0289724 | FBpp0292244 | Ankyrin, isoform B; Ankyrin (Ank) encodes protein that is recruited to the plasma membrane by its association with the product of beta-Spec. It also binds to the adhesion protein encoded by Nrg leading to accumulation of the products of Ank and beta-Spec at sites of cell-cell adhesion. | Ankyrin 2, isoform U; Ankyrin 2 (Ank2) encodes a cytoskeletal binding protein required for proper function of the product of beta-Spec via direct interaction. It contributes to the regulation of short-term memory, sound perception, microtubule cytoskeleton and neuromuscular junction development and synapsis. | 0.902 |
Ank | Moe | FBpp0289724 | FBpp0071213 | Ankyrin, isoform B; Ankyrin (Ank) encodes protein that is recruited to the plasma membrane by its association with the product of beta-Spec. It also binds to the adhesion protein encoded by Nrg leading to accumulation of the products of Ank and beta-Spec at sites of cell-cell adhesion. | Moesin/ezrin/radixin homolog 1; Involved in connections of major cytoskeletal structures to the plasma membrane. Together with wgn, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr. In the nucleus, recruited to sites of active transcription by RNA polymerase II where it has a role in nuclear mRNA export together with the mRNA export factor PCID2 and other messenger ribonucleoprotein (mRNP) particles. | 0.560 |
Ank | alpha-Spec | FBpp0289724 | FBpp0305100 | Ankyrin, isoform B; Ankyrin (Ank) encodes protein that is recruited to the plasma membrane by its association with the product of beta-Spec. It also binds to the adhesion protein encoded by Nrg leading to accumulation of the products of Ank and beta-Spec at sites of cell-cell adhesion. | Spectrin alpha chain; Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Essential for larval survival and development. Stabilizes cell to cell interactions that are critical for the maintenance of cell shape and subcellular organization within embryonic tissues. Lva and spectrin may form a Golgi-based scaffold that mediates interaction of Golgi bodies with microtubules and facilitates Golgi- derived membrane secretion [...] | 0.731 |
Ank | hts | FBpp0289724 | FBpp0301121 | Ankyrin, isoform B; Ankyrin (Ank) encodes protein that is recruited to the plasma membrane by its association with the product of beta-Spec. It also binds to the adhesion protein encoded by Nrg leading to accumulation of the products of Ank and beta-Spec at sites of cell-cell adhesion. | Hu li tai shao (hts) encodes an adducin homolog that is associated with the plasma membrane cytoskeleton, fusome and oocyte ring canals. It has essential functions in muscle, nerve and other tissues, and is required for fertility in males and females; Belongs to the aldolase class II family. Adducin subfamily. | 0.607 |
Ank | kst | FBpp0289724 | FBpp0289294 | Ankyrin, isoform B; Ankyrin (Ank) encodes protein that is recruited to the plasma membrane by its association with the product of beta-Spec. It also binds to the adhesion protein encoded by Nrg leading to accumulation of the products of Ank and beta-Spec at sites of cell-cell adhesion. | Karst, isoform E; Karst (kst) encodes a protein that, together with the product of alpha-Spec, crosslinks F-actin and acts as a molecular scaffold. It is recruited to the apical membrane of epithelial cells by the apical determinant encoded by crb. The roles of the product of kst include endosomal trafficking, cell adhesion, cell signaling and growth control. | 0.969 |
Ank | nompC | FBpp0289724 | FBpp0312558 | Ankyrin, isoform B; Ankyrin (Ank) encodes protein that is recruited to the plasma membrane by its association with the product of beta-Spec. It also binds to the adhesion protein encoded by Nrg leading to accumulation of the products of Ank and beta-Spec at sites of cell-cell adhesion. | No mechanoreceptor potential C (nompC) encodes a pore-forming subunit for a mechanosensitive non-selective cation channel. It belongs to the TRP channel family and is expressed in peripheral sensory neurons. It senses gentle touch and regulates locomotion in larval body wall neurons. In the adult, the product of nompC is involved in hearing transduction in the Johnston's organ. | 0.441 |
Ank2 | Ank | FBpp0292244 | FBpp0289724 | Ankyrin 2, isoform U; Ankyrin 2 (Ank2) encodes a cytoskeletal binding protein required for proper function of the product of beta-Spec via direct interaction. It contributes to the regulation of short-term memory, sound perception, microtubule cytoskeleton and neuromuscular junction development and synapsis. | Ankyrin, isoform B; Ankyrin (Ank) encodes protein that is recruited to the plasma membrane by its association with the product of beta-Spec. It also binds to the adhesion protein encoded by Nrg leading to accumulation of the products of Ank and beta-Spec at sites of cell-cell adhesion. | 0.902 |
Ank2 | Moe | FBpp0292244 | FBpp0071213 | Ankyrin 2, isoform U; Ankyrin 2 (Ank2) encodes a cytoskeletal binding protein required for proper function of the product of beta-Spec via direct interaction. It contributes to the regulation of short-term memory, sound perception, microtubule cytoskeleton and neuromuscular junction development and synapsis. | Moesin/ezrin/radixin homolog 1; Involved in connections of major cytoskeletal structures to the plasma membrane. Together with wgn, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr. In the nucleus, recruited to sites of active transcription by RNA polymerase II where it has a role in nuclear mRNA export together with the mRNA export factor PCID2 and other messenger ribonucleoprotein (mRNP) particles. | 0.547 |
Ank2 | alpha-Spec | FBpp0292244 | FBpp0305100 | Ankyrin 2, isoform U; Ankyrin 2 (Ank2) encodes a cytoskeletal binding protein required for proper function of the product of beta-Spec via direct interaction. It contributes to the regulation of short-term memory, sound perception, microtubule cytoskeleton and neuromuscular junction development and synapsis. | Spectrin alpha chain; Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Essential for larval survival and development. Stabilizes cell to cell interactions that are critical for the maintenance of cell shape and subcellular organization within embryonic tissues. Lva and spectrin may form a Golgi-based scaffold that mediates interaction of Golgi bodies with microtubules and facilitates Golgi- derived membrane secretion [...] | 0.490 |
Ank2 | hts | FBpp0292244 | FBpp0301121 | Ankyrin 2, isoform U; Ankyrin 2 (Ank2) encodes a cytoskeletal binding protein required for proper function of the product of beta-Spec via direct interaction. It contributes to the regulation of short-term memory, sound perception, microtubule cytoskeleton and neuromuscular junction development and synapsis. | Hu li tai shao (hts) encodes an adducin homolog that is associated with the plasma membrane cytoskeleton, fusome and oocyte ring canals. It has essential functions in muscle, nerve and other tissues, and is required for fertility in males and females; Belongs to the aldolase class II family. Adducin subfamily. | 0.619 |
Ank2 | kst | FBpp0292244 | FBpp0289294 | Ankyrin 2, isoform U; Ankyrin 2 (Ank2) encodes a cytoskeletal binding protein required for proper function of the product of beta-Spec via direct interaction. It contributes to the regulation of short-term memory, sound perception, microtubule cytoskeleton and neuromuscular junction development and synapsis. | Karst, isoform E; Karst (kst) encodes a protein that, together with the product of alpha-Spec, crosslinks F-actin and acts as a molecular scaffold. It is recruited to the apical membrane of epithelial cells by the apical determinant encoded by crb. The roles of the product of kst include endosomal trafficking, cell adhesion, cell signaling and growth control. | 0.961 |
CG13192 | kst | FBpp0087138 | FBpp0289294 | IP10750p; It is involved in the biological process described with: social behavior. | Karst, isoform E; Karst (kst) encodes a protein that, together with the product of alpha-Spec, crosslinks F-actin and acts as a molecular scaffold. It is recruited to the apical membrane of epithelial cells by the apical determinant encoded by crb. The roles of the product of kst include endosomal trafficking, cell adhesion, cell signaling and growth control. | 0.854 |
Elk | kst | FBpp0085981 | FBpp0289294 | Eag-like K[+] channel, isoform A; Voltage-gated potassium channel activity; voltage-gated cation channel activity. It is involved in the biological process described with: regulation of membrane potential; potassium ion transmembrane transport; potassium ion transport. | Karst, isoform E; Karst (kst) encodes a protein that, together with the product of alpha-Spec, crosslinks F-actin and acts as a molecular scaffold. It is recruited to the apical membrane of epithelial cells by the apical determinant encoded by crb. The roles of the product of kst include endosomal trafficking, cell adhesion, cell signaling and growth control. | 0.630 |
Moe | Ank | FBpp0071213 | FBpp0289724 | Moesin/ezrin/radixin homolog 1; Involved in connections of major cytoskeletal structures to the plasma membrane. Together with wgn, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr. In the nucleus, recruited to sites of active transcription by RNA polymerase II where it has a role in nuclear mRNA export together with the mRNA export factor PCID2 and other messenger ribonucleoprotein (mRNP) particles. | Ankyrin, isoform B; Ankyrin (Ank) encodes protein that is recruited to the plasma membrane by its association with the product of beta-Spec. It also binds to the adhesion protein encoded by Nrg leading to accumulation of the products of Ank and beta-Spec at sites of cell-cell adhesion. | 0.560 |
Moe | Ank2 | FBpp0071213 | FBpp0292244 | Moesin/ezrin/radixin homolog 1; Involved in connections of major cytoskeletal structures to the plasma membrane. Together with wgn, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr. In the nucleus, recruited to sites of active transcription by RNA polymerase II where it has a role in nuclear mRNA export together with the mRNA export factor PCID2 and other messenger ribonucleoprotein (mRNP) particles. | Ankyrin 2, isoform U; Ankyrin 2 (Ank2) encodes a cytoskeletal binding protein required for proper function of the product of beta-Spec via direct interaction. It contributes to the regulation of short-term memory, sound perception, microtubule cytoskeleton and neuromuscular junction development and synapsis. | 0.547 |
Moe | crb | FBpp0071213 | FBpp0293268 | Moesin/ezrin/radixin homolog 1; Involved in connections of major cytoskeletal structures to the plasma membrane. Together with wgn, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr. In the nucleus, recruited to sites of active transcription by RNA polymerase II where it has a role in nuclear mRNA export together with the mRNA export factor PCID2 and other messenger ribonucleoprotein (mRNP) particles. | Protein crumbs; Plays a central role in cell polarity establishment. Participates in the assembly, positioning and maintenance of adherens junctions via its interaction with the SAC complex. Controls the coalescence of the spots of zonula adherens (ZA) into a adhesive ring around the cells. It may act as a signal. Involved in morphogenesis of the photoreceptor rhabdomere, for positioning and growth of rhabdomere and AJ during the crucial period of photoreceptor extension along the proximodistal axis of the retina. Component of the crb-galla-Xpd (CGX) complex which is essential for prop [...] | 0.996 |
Moe | kst | FBpp0071213 | FBpp0289294 | Moesin/ezrin/radixin homolog 1; Involved in connections of major cytoskeletal structures to the plasma membrane. Together with wgn, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr. In the nucleus, recruited to sites of active transcription by RNA polymerase II where it has a role in nuclear mRNA export together with the mRNA export factor PCID2 and other messenger ribonucleoprotein (mRNP) particles. | Karst, isoform E; Karst (kst) encodes a protein that, together with the product of alpha-Spec, crosslinks F-actin and acts as a molecular scaffold. It is recruited to the apical membrane of epithelial cells by the apical determinant encoded by crb. The roles of the product of kst include endosomal trafficking, cell adhesion, cell signaling and growth control. | 0.678 |
alpha-Spec | Ank | FBpp0305100 | FBpp0289724 | Spectrin alpha chain; Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Essential for larval survival and development. Stabilizes cell to cell interactions that are critical for the maintenance of cell shape and subcellular organization within embryonic tissues. Lva and spectrin may form a Golgi-based scaffold that mediates interaction of Golgi bodies with microtubules and facilitates Golgi- derived membrane secretion [...] | Ankyrin, isoform B; Ankyrin (Ank) encodes protein that is recruited to the plasma membrane by its association with the product of beta-Spec. It also binds to the adhesion protein encoded by Nrg leading to accumulation of the products of Ank and beta-Spec at sites of cell-cell adhesion. | 0.731 |
alpha-Spec | Ank2 | FBpp0305100 | FBpp0292244 | Spectrin alpha chain; Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Essential for larval survival and development. Stabilizes cell to cell interactions that are critical for the maintenance of cell shape and subcellular organization within embryonic tissues. Lva and spectrin may form a Golgi-based scaffold that mediates interaction of Golgi bodies with microtubules and facilitates Golgi- derived membrane secretion [...] | Ankyrin 2, isoform U; Ankyrin 2 (Ank2) encodes a cytoskeletal binding protein required for proper function of the product of beta-Spec via direct interaction. It contributes to the regulation of short-term memory, sound perception, microtubule cytoskeleton and neuromuscular junction development and synapsis. | 0.490 |
alpha-Spec | crb | FBpp0305100 | FBpp0293268 | Spectrin alpha chain; Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Essential for larval survival and development. Stabilizes cell to cell interactions that are critical for the maintenance of cell shape and subcellular organization within embryonic tissues. Lva and spectrin may form a Golgi-based scaffold that mediates interaction of Golgi bodies with microtubules and facilitates Golgi- derived membrane secretion [...] | Protein crumbs; Plays a central role in cell polarity establishment. Participates in the assembly, positioning and maintenance of adherens junctions via its interaction with the SAC complex. Controls the coalescence of the spots of zonula adherens (ZA) into a adhesive ring around the cells. It may act as a signal. Involved in morphogenesis of the photoreceptor rhabdomere, for positioning and growth of rhabdomere and AJ during the crucial period of photoreceptor extension along the proximodistal axis of the retina. Component of the crb-galla-Xpd (CGX) complex which is essential for prop [...] | 0.632 |