STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG4678Uncharacterized protein, isoform E; Metallocarboxypeptidase activity; zinc ion binding; serine-type carboxypeptidase activity. It is involved in the biological process described with: peptide metabolic process; protein processing. (527 aa)    
Predicted Functional Partners:
e
LP19442p; Ebony (e) encodes a protein that links beta-alanine to biogenic amines like dopamine or histamine. It controls the amount of free biogenic amine, e.g. of dopamine in cuticle formation and of histamine in visual signal transduction of the eye. It is also involved in behavioral rhythmicity.
      
 0.605
Yippee
Protein yippee; Metal ion binding.
 
 
    0.538
amon
Amontillado (amon) encodes a member of the Prohormone Convertase (PC) family of proteolytic enzymes. PCs generally recognize conserved basic amino acid sequences within protein precursors to direct catalysis of specific cleavage. amon product directly cleaves sli protein and may also target the propeptide encoded by Akh. It is also required for the production of bioactive neuropeptide hormones (e.g. those encoded by Hug, Crz, Ms, Capa and sNPF); Belongs to the peptidase S8 family.
   
  
 0.530
Syt4
Synaptotagmin 4 (Syt4) encodes a vesicular calcium binding protein implicated in retrograde signaling at synapses. It is proposed to regulate calcium-dependent cargo trafficking within the postsynaptic compartment.
   
  
 0.461
CG3108
LP17541p; Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.
  
   
 0.459
CG4017
RH39904p; Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.
  
   
 0.453
CG8564
Uncharacterized protein, isoform C; Zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis.
  
   
 0.453
RYa
RYamide neuropeptides; Neuropeptides RYamide-1 and RYamide-2 are ligands for the G- protein coupled receptor RYa-R. May suppress feeding behavior.
      
 0.449
CG12374
RH58587p; Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.
  
   
 0.436
CG17633
Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis; Belongs to the peptidase M14 family.
  
   
 0.432
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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