STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp6a20Probable cytochrome P450 6a20; Cyp6a20 (Cyp6a20) encodes a protein that may function to degrade aggression-promoting pheromones based on indirect observations such as its expression pattern and the increased aggressive behavior shown in Cyp6a20 mutants. (501 aa)    
Predicted Functional Partners:
GstE9
Putative glutathione S-transferase; Glutathione S transferase E9 (GstE9) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
   
  
 0.708
CG6675
Uncharacterized protein, isoform B; Lipase activity; carboxylic ester hydrolase activity. It is involved in the biological process described with: lipid catabolic process.
   
 
 0.630
GstE1
Glutathione S transferase E1 (GstE1) encodes an enzyme involved in glutathione metabolic processes and response to heat.
   
  
 0.585
GstD9
Glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process.
   
  
 0.560
GstD3
Inactive glutathione S-transferase D3; Has no glutathione S-transferase activity. Belongs to the GST superfamily. Delta family.
   
  
 0.550
Ugt37D1
UDP-glycosyltransferase family 37 member D1, isoform A; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity.
   
 
 0.537
CG9360
RH17287p; 17-beta-ketosteroid reductase activity; estradiol 17-beta-dehydrogenase activity; 3-keto sterol reductase activity; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.533
GstE7
Glutathione S transferase E7 (GstE7) encodes a cytosolic enzyme that functions in detoxication. It has high catalytic activity with various isothiocyanates and the toxic environmental pollutants 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (DNT).
   
  
 0.510
CG31189
Uncharacterized protein.
   
  
 0.502
CG42825
GH19118p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport.
   
 
 0.500
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.