STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM216Transmembrane protein 216, isoform A; It is involved in the biological process described with: non-motile cilium assembly; cilium assembly. (136 aa)    
Predicted Functional Partners:
B9d1
B9 domain-containing protein 1; Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia. Required for ciliary structure and function.
      
 0.979
Cc2d2a
Coiled-coil and C2 domain-containing protein 2A; Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia (Probable). Required for ciliary structure and function (By similarity).
      
 0.967
B9d2
B9 domain-containing protein 2; Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia. Has a role in ciliary structure and function.
      
 0.962
cep290
Centrosomal protein cep290; Essential for ciliogenesis in sensory neurons and germ cells. During neuron and spermatocyte ciliogenesis, plays a role in transition zone assembly where it is required for the formation of diverse connections between microtubules and between microtubules and the membrane.
      
 0.939
Mks1
Meckel syndrome type 1 protein homolog; Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia. Required for ciliary structure and function.
      
 0.761
IFT46
Intraflagellar transport 46; It is involved in the biological process described with: intraciliary transport; cilium assembly.
      
 0.691
CG4975
Uncharacterized protein, isoform C.
      
 0.669
Oseg6
Outer segment 6; It is involved in the biological process described with: intraciliary retrograde transport; cilium assembly; non-motile cilium assembly.
   
  
 0.647
CG17658
FI21801p1.
   
  
 0.628
IFT57
Intraflagellar transport protein 57 homolog; Required for the formation of cilia; Belongs to the IFT57 family.
      
 0.572
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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