| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rab3 | Rim | FBpp0087352 | FBpp0293558 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. | 0.997 |
| Rab3 | Rop | FBpp0087352 | FBpp0302752 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Protein ROP; May be a component of one of the vesicle trafficking pathways. May interact functionally with Ras2 protein. | 0.723 |
| Rab3 | Snap25 | FBpp0087352 | FBpp0110435 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Synaptosomal-associated protein 25kDa (Snap25) encodes a synaptic target SNARE protein and a component of SNARE protein complexes known to function in neurotransmitter release. It functions in synaptic transmission in larvae and is essential in adults; Belongs to the SNAP-25 family. | 0.863 |
| Rab3 | Syb | FBpp0087352 | FBpp0271782 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Synaptobrevin; Unknown, but synaptobrevins are presumed to be involved in targeting and fusion of synaptic vesicles with the presynaptic membrane as well as in neurotransmitter release. | 0.939 |
| Rab3 | Syt1 | FBpp0087352 | FBpp0077410 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Synaptotagmin 1; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. | 0.984 |
| Rab3 | Syx1A | FBpp0087352 | FBpp0292260 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Syntaxin-1A; Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Required for coordinated peristaltic contractions. Recruited by Unc-13-4B to secretory lysosome-related organelles (SLs) that are essential for tracheal lumen fusion between previously separate tracheal branches (anastomosis). Possibly promotes the intracellular fusion of the extending tracheal stalk cell lumens [...] | 0.777 |
| Rab3 | Tomosyn | FBpp0087352 | FBpp0073511 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Tomosyn, isoform C; Tomosyn (Tomosyn) encodes a protein involved in long-term memory and neuromuscular synaptic transmission. | 0.520 |
| Rab3 | alphaSnap | FBpp0087352 | FBpp0074609 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Also between the endosome and phagosome. | 0.462 |
| Rab3 | cpx | FBpp0087352 | FBpp0307585 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Complexin (cpx) encodes a presynaptic cytosolic protein that regulates SNARE complex assembly and fuction. It has both positive and negative roles in synaptic transmission, serving as the synaptic vesicle fusion clamp and as an activator of evoked release; Belongs to the complexin/synaphin family. | 0.847 |
| Rab3 | unc-13 | FBpp0087352 | FBpp0300963 | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | Unc-13, isoform E; Unc-13 (unc-13) encodes a protein involved in synaptic vesicle exocytosis. | 0.985 |
| Rim | Rab3 | FBpp0293558 | FBpp0087352 | Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | 0.997 |
| Rim | Rop | FBpp0293558 | FBpp0302752 | Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. | Protein ROP; May be a component of one of the vesicle trafficking pathways. May interact functionally with Ras2 protein. | 0.929 |
| Rim | Snap25 | FBpp0293558 | FBpp0110435 | Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. | Synaptosomal-associated protein 25kDa (Snap25) encodes a synaptic target SNARE protein and a component of SNARE protein complexes known to function in neurotransmitter release. It functions in synaptic transmission in larvae and is essential in adults; Belongs to the SNAP-25 family. | 0.777 |
| Rim | Syb | FBpp0293558 | FBpp0271782 | Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. | Synaptobrevin; Unknown, but synaptobrevins are presumed to be involved in targeting and fusion of synaptic vesicles with the presynaptic membrane as well as in neurotransmitter release. | 0.916 |
| Rim | Syt1 | FBpp0293558 | FBpp0077410 | Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. | Synaptotagmin 1; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. | 0.746 |
| Rim | Syx1A | FBpp0293558 | FBpp0292260 | Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. | Syntaxin-1A; Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Required for coordinated peristaltic contractions. Recruited by Unc-13-4B to secretory lysosome-related organelles (SLs) that are essential for tracheal lumen fusion between previously separate tracheal branches (anastomosis). Possibly promotes the intracellular fusion of the extending tracheal stalk cell lumens [...] | 0.892 |
| Rim | Tomosyn | FBpp0293558 | FBpp0073511 | Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. | Tomosyn, isoform C; Tomosyn (Tomosyn) encodes a protein involved in long-term memory and neuromuscular synaptic transmission. | 0.609 |
| Rim | cpx | FBpp0293558 | FBpp0307585 | Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. | Complexin (cpx) encodes a presynaptic cytosolic protein that regulates SNARE complex assembly and fuction. It has both positive and negative roles in synaptic transmission, serving as the synaptic vesicle fusion clamp and as an activator of evoked release; Belongs to the complexin/synaphin family. | 0.910 |
| Rim | unc-13 | FBpp0293558 | FBpp0300963 | Rab3 interacting molecule (Rim) encodes a scaffolding protein at the synaptic active zone, with important roles in promoting neurotransmitter release. | Unc-13, isoform E; Unc-13 (unc-13) encodes a protein involved in synaptic vesicle exocytosis. | 0.999 |
| Rop | Rab3 | FBpp0302752 | FBpp0087352 | Protein ROP; May be a component of one of the vesicle trafficking pathways. May interact functionally with Ras2 protein. | Ras-related protein Rab-3; Rab3 (Rab3) encodes a member of a large family of Ras-like small GTPases. Localized primarily at the synapse, Rab3 product is involved in mechanisms that control synaptic development and function, including the regulation of active zone protein composition at the neuromuscular junction. | 0.723 |